PE/Cyanine7 anti-mouse/human CD11b Antibody

Pricing & Availability
Clone
M1/70 (See other available formats)
Regulatory Status
RUO
Other Names
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
M1slash70_PECy7_042706
C57BL/6 mouse bone marrow cells were stained with CD11b (clone M1/70) PE/Cyanine7 (filled histogram) or rat IgG2b, κ PE/Cyanine7 isotype control (open histogram) (gated on total cells).
  • M1slash70_PECy7_042706
    C57BL/6 mouse bone marrow cells were stained with CD11b (clone M1/70) PE/Cyanine7 (filled histogram) or rat IgG2b, κ PE/Cyanine7 isotype control (open histogram) (gated on total cells).
Compare all formats See PE/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
101215 25 µg 70€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
101216 100 µg 169€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human, Cynomolgus, Rhesus
Reported Reactivity
Chimpanzee, Baboon, Rabbit
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
C57BL/10 splenocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F).

Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1,4, in vitro blocking3,9,12, depletion2,8, immunofluorescence microscopy6,7,10, immunohistochemistry of acetone-fixed frozen sections5,11-13, and spatial biology (IBEX)35,36. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).

Additional Product Notes
BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
Application References

(PubMed link indicates BioLegend citation)
  1. Springer T, et al. 1978. Eur. J. Immunol. 8:539. (IP)
  2. Ault K and Springer T. 1981. J. Immunol. 126:359. (Deplete)
  3. Springer TA, et al. 1982. Immunol. Rev. 68:171. (Block)
  4. Ho MK and Springer TA. 1983. J. Biol. Chem. 258:2766. (IP)
  5. Flotte TJ, et al. 1983. Am. J. Pathol. 111:112. (IHC)
  6. Noel GJ, et al. 1990. J. Clin. Invest. 85:208. (IF)
  7. Allen LA and Aderem A. 1996. J. Exp. Med. 184:627 (IF)
  8. D'Amico A and Wu L. 2003. J. Exp. Med. 198:293. (Deplete)
  9. Brickson SJ, et al. 2003. Appl Physiol. 95:969. (Block)
  10. Clatworthy MR and Smith KG. 2004. J. Exp. Med. 199:717. (IF)
  11. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  12. Zhang Y, et al. 2002. J. Immunol. 168:3088. (IHC)
  13. Iwasaki A and Kelsall BL. 2001. J. Immunol. 166:4884 (IHC, FC)
  14. Tailleux L. 2003. J. Exp. Med. 197:121. (Block, FC)
  15. Olver S, et al. 2006. Cancer Research 66:571. (FC)
  16. Tan SL, et al. 2006. J. Immunol. 176:2872. (FC) PubMed
  17. Ponomarev ED, et al. 2006. J. Immunol. 176:1402. (FC)
  18. Dzhagalov I, et al. 2007. Blood 109:1620. (FC)
  19. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  20. Rasmussen JW, et al. 2006. Infect. Immun.74:6590. PubMed
  21. Napimoga MH, et al. 2008. J. Immunol. 180:609. PubMed
  22. Elqaraz-Carmon V, et al. 2008. J. Lipid. Res. 49:1894. PubMed
  23. Kim DD, et al. 2008. Blood 112:1109. PubMed
  24. Guo Y, et al. 2008. Blood 112:480. PubMed
  25. Norian LA, et al. 2009. Cancer Res. 69:3086. (FC) PubMed
  26. Baumgartner CK, et al. 2010. J. Immunol. 184:573. PubMed
  27. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  28. Whiteland J, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
  29. Weber GF, et al. 2014. J Exp Med. 211:1243. PubMed
  30. Ashok A, et al. 2015. Toxicol Sci. 143:64. PubMed
  31. Price PJ, et al. 2015. J Immunol. 194:1164. PubMed
  32. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  33. Ferreira R, et al. 2016. J Infect Dis. 213: 669 - 673. PubMed
  34. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  35. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  36. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Parsons M, et al. 2014. J Immunol. 192:1361. PubMed
  2. Tebartz C, et al. 2015. J Immunol. 194:1100. PubMed
  3. Quispe Calla N, et al. 2016. Sci Rep. 6:37723. PubMed
  4. D'Alessandro G, et al. 2020. Eur J Immunol. 50:705. PubMed
  5. DeSouza-Vieira T, et al. 2020. Cell Rep. 33:108317. PubMed
  6. Gogoi H, et al. 2020. Front Immunol. 1.620833333. PubMed
  7. Liu K, et al. 2021. Cell Metabolism. 33(3):666-675.e4. PubMed
  8. Hatzi K, et al. 2019. Nat Immunol. 20:86. PubMed
  9. Tran NT, et al. 2019. Cell Rep. 28:3510. PubMed
  10. Lin C et al. 2019. Immunity. 50(1):137-151 . PubMed
  11. Okunuki Y, et al. 2018. Proc Natl Acad Sci U S A. 115:E6264. PubMed
  12. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  13. Wang L, et al. 2021. J Nanobiotechnology. 19:56. PubMed
  14. Kuo PC, et al. 2021. Brain Commun. 3:fcab187. PubMed
  15. Cheresh P, et al. 2021. Int J Mol Sci. 22:. PubMed
  16. Deng R, et al. 2022. Adv Sci (Weinh). 9:e2103343. PubMed
  17. Odom CV, et al. 2021. J Immunol. 207:1891. PubMed
  18. Correa S, et al. 2020. ACS Nano. 2224:14. PubMed
  19. Kim JS, et al. 2020. Immunity. 54(1):176-190.e7. PubMed
  20. Gazit R, et al. 2014. J Exp Med. 211:1315. PubMed
  21. Giorgetti E, et al. 2020. Cell Reports. 29(6):1539-1554.e7.. PubMed
  22. Thelin MA, et al. 2017. Diabetes. 66:2220. PubMed
  23. Zhang LJ, et al. 2019. Immunity. 50:121. PubMed
  24. Abels ER et al. 2019. Cell Rep. 28(12):3105-3119 . PubMed
  25. Frisbee AL, et al. 2019. Nat Commun. 10:2712. PubMed
  26. Groza D, et al. 2018. Oncoimmunology. 7:e1424676. PubMed
  27. Alissafi T, et al. 2018. J Clin Invest. 128:3840. PubMed
  28. Iwamoto H et al. 2018. Cell metabolism. 28(1):104-117 . PubMed
  29. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  30. Kitagawa S, et al. 2022. NPJ Vaccines. 7:115. PubMed
  31. Rodrigues M, et al. 2022. Biochem J. 479:1891. PubMed
  32. Jung MY, et al. 2022. Neurooncol Adv. 4:vdac017. PubMed
  33. Schönberger K, et al. 2022. Cell Stem Cell. 29:131. PubMed
  34. Di Martile M, et al. 2020. J Immunother Cancer. 8:. PubMed
  35. Sharma GP, et al. 2021. PLoS One. 16:e0259042. PubMed
  36. Li Z, et al. 2021. Immunology. 163:105. PubMed
  37. Radovanovic I, et al. 2014. J Immunol. 193:1290. PubMed
  38. Zasłona Z, et al. 2014. J Immunol. 193:4245. PubMed
  39. Zheng W, et al. 2021. Wellcome Open Research. 6:52. PubMed
  40. Mogilenko DA, et al. 2020. Immunity. 54(1):99-115.e12. PubMed
  41. Riether C, et al. 2021. Cell Reports. 34(4):108663. PubMed
  42. Yu K, et al. 2021. Cell Reports. 35(12):109273. PubMed
  43. Kurelac I, et al. 2019. Nat Commun. 10:903. PubMed
  44. Kobayashi Y, et al. 2018. PLoS One. 13:e0195008. PubMed
  45. Delás MJ, et al. 2019. Cell Rep. 27:719. PubMed
  46. Wei H, et al. 2021. Malar J. 20:89. PubMed
  47. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 5:64. PubMed
  48. Hickey A, et al. 2021. Front Microbiol. 12:653587. PubMed
  49. Morgan PK, et al. 2021. J Biol Chem. 297:101341. PubMed
  50. Yang C, et al. 2021. J Immunother Cancer. 9:. PubMed
  51. Piepke M, et al. 2021. J Neuroinflammation. 18:265. PubMed
  52. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  53. Chen T, et al. 2021. JCI Insight. 6:. PubMed
  54. Shen H, et al. 2015. Infect Immun . 83: 2694 - 2704. PubMed
  55. Periasamy S, et al. 2017. Nat Commun. 8:15564. PubMed
  56. Saggu G, et al. 2018. Nat Commun. 9:5058. PubMed
  57. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  58. Bowers E, et al. 2018. Nat Med. 24:95. PubMed
  59. Yang X, et al. 2020. Blood Sci. 2:89. PubMed
  60. Deslyper G, et al. 2021. Parasitology. 148:539. PubMed
  61. Martin R, et al. 2014. J Leukoc Biol. 96:151. PubMed
  62. Shemer A, et al. 2020. Immunity. 53(5):1033-1049.e7. PubMed
  63. Yamamoto K, et al. 2021. Cell Reports. 36(8):109576. PubMed
  64. Uroda T, et al. 2020. Nat Protoc. 15:2107. PubMed
  65. Akhmetzyanova ER, et al. 2019. Front Cell Neurosci. 12:507. PubMed
  66. Lubkin A et al. 2019. Cell host & microbe. 25(3):463-470 . PubMed
  67. Gibson EM, et al. 2019. Cell. 176:43:00. PubMed
  68. Juttukonda LJ, et al. 2017. Cell Host Microbe. 22:531. PubMed
  69. LaFleur MW, et al. 2019. Nat Immunol. 20:1335. PubMed
  70. Somerville TD, et al. 2020. eLife. 9:e53381.. PubMed
  71. Go DM, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:715. PubMed
  72. Park JA, et al. 2021. J Hematol Oncol. 14:142. PubMed
  73. Zong L, et al. 2021. NPJ Aging Mech Dis. 7:25. PubMed
  74. Almutairi F, et al. 2021. Front Immunol. 12:772288. PubMed
  75. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  76. Royzman D, et al. 2022. Front Immunol. 13:1012647. PubMed
  77. Ellis G, et al. 2015. EMBO Rep. 16: 1203-1218. PubMed
  78. Vazquez S, et al. 2015. Exp Hematol. 43: 578-585. PubMed
  79. Shade K, et al. 2015. J Exp Med. 212:457. PubMed
  80. Sasaki K, et al. 2019. Nat Commun. 10:3878. PubMed
  81. Angelidis I, et al. 2019. Nat Commun. 10:963. PubMed
  82. Xu X, et al. 2021. J Nanobiotechnology. 19:376. PubMed
  83. Walker FC, et al. 2021. PLoS Pathog. 17:e1009402. PubMed
  84. Johansen AZ, et al. 2022. Pharmaceutics. 14:. PubMed
  85. Liu Y, et al. 2022. Nat Commun. 13:2665. PubMed
  86. Beauchamp EM, et al. 2021. Blood Cancer Discov. 6:. PubMed
  87. Dodagatta-Marri E, et al. 2021. Cell Rep. 36:109309. PubMed
  88. Super M, et al. 2021. Nat Biomed Eng. Online ahead of print. PubMed
  89. Kulkarni NN, et al. 2021. J Biol Chem. 297:100828. PubMed
  90. Jia X, et al. 2021. Front Cell Dev Biol. 9:685522. PubMed
  91. Klopfenstein N, et al. 2021. PLoS Pathog. 17:e1009387. PubMed
  92. Koh F, et al. 2015. Proc Natl Acad Sci U S A. 112:1734. PubMed
  93. Kohn M, et al. 2021. Front Immunol. 580594:12. PubMed
  94. Vasilijevic J, et al. 2017. PLoS Pathog. 13:e1006650. PubMed
  95. Meeks K, et al. 2009. J Immunol. 183:8026. PubMed
  96. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  97. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  98. Wang L, et al. 2021. Cancer Immunol Res. 9:348. PubMed
  99. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  100. Shin JE, et al. 2021. Heliyon. 7:e08433. PubMed
  101. Aegerter H, et al. 2020. Nat Immunol. 0.975694444. PubMed
  102. Zhang S, et al. 2020. Front Immunol. 1.757638889. PubMed
  103. Kirschbaum K, et al. 2016. Proc Natl Acad Sci U S A. 113: 13227 - 13232. PubMed
  104. Varol D et al. 2017. Immunity. 46(6):1030-1044 . PubMed
  105. Snell LM, et al. 2018. Immunity. 49:678. PubMed
  106. Amo-Aparicio J, et al. 2021. Theranostics. 11:9805. PubMed
  107. Mansouri S, et al. 2021. J Immunol. 206:2233. PubMed
  108. Goldman E, et al. 2021. Cells. 10:. PubMed
  109. Dokoshi T, et al. 2021. J Clin Invest. 131:. PubMed
  110. Pan YC, et al. 2021. Mol Ther Oncolytics. 20:175. PubMed
  111. Xie Z, et al. 2020. Light Sci Appl. 0.486805556. PubMed
  112. Gomzikova MO, et al. 2020. Sci Rep. 10:10740. PubMed
  113. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  114. Okubo K, et al. 2021. Cell Reports. 35(7):109142. PubMed
  115. Gozgit JM, et al. 2021. Cancer Cell. :. PubMed
  116. Kooreman NG et al. 2018. Cell stem cell. 22(4):501-513 . PubMed
  117. Proto JD et al. 2018. Immunity. 49(4):666-677 . PubMed
  118. Secondini C, et al. 2017. Oncoimmunology. 6:e1316437. PubMed
  119. Huang YL, et al. 2021. Commun Biol. 4:229. PubMed
  120. Littwitz-Salomon E, et al. 2021. Nat Commun. 12:5376. PubMed
  121. Synn CB, et al. 2022. Clin Transl Immunology. 11:e1364. PubMed
  122. Jia Q, et al. 2021. Theranostics. 4699:11. PubMed
  123. Dobosz E, et al. 2021. Dis Model Mech. :14. PubMed
  124. Mulas F, et al. 2020. Cell Mol Immunol. . PubMed
  125. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  126. Bambouskova M, et al. 2021. Cell Reports. 34(10):108756. PubMed
  127. Ringel AE, et al. 2020. Cell. 183(7):1848-1866.e26. PubMed
  128. Pérez-Girón J, et al. 2015. J Vis Exp. 100: 52803. PubMed
  129. Suresh MV, et al. 2019. JCI Insight. 4:e133103. PubMed
  130. Patel S, et al. 2019. Viruses. 0.877083333. PubMed
  131. Bradley KC, et al. 2019. Cell Rep. 28:245. PubMed
  132. Kumar MP, et al. 2018. Cell Rep. 25:1458. PubMed
  133. Steuerman Y et al. 2018. Cell systems. 6(6):679-691 . PubMed
  134. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  135. Uddin MJ, et al. 2022. Mucosal Immunol. 15:165. PubMed
  136. Wang D, et al. 2021. Nat Commun. 12:2674. PubMed
  137. Boulay A, et al. 2015. J Neurosci. 35:4427. PubMed
  138. Trefzer A, et al. 2021. Cell Reports. 34(6):108748. PubMed
  139. Lim CX, et al. 2020. Cell Rep. 3793:30. PubMed
  140. Li Z, et al. 2018. Front Immunol. 9:347. PubMed
  141. Marcus A et al. 2018. Immunity. 49(4):754-763 . PubMed
  142. Van Winkle JA et al. 2018. Cell host & microbe. 24(5):665-676 . PubMed
  143. LaFleur MW, et al. 2019. Nat Commun. 10:1668. PubMed
  144. Wilson DH, et al. 2020. Nat Commun. 0.767361111. PubMed
  145. Tran NT, et al. 2020. STAR Protocols. 1(1):100028. PubMed
  146. Endoh M, et al. 2020. Cell Reports. 30(6):1823-1834. PubMed
  147. Li H, et al. 2020. Nature. 584:274. PubMed
  148. Sibilio A, et al. 2022. iScience. 25:103790. PubMed
  149. Dey S, et al. 2020. J Immunother Cancer. 8:. PubMed
  150. Shen M, et al. 2022. Nat Cancer. 3:60. PubMed
  151. Liu H, et al. 2022. Front Pharmacol. 13:949316. PubMed
  152. Frenis K, et al. 2021. Basic Res Cardiol. 31:116. PubMed
  153. Crouse B, et al. 2020. NPJ Vaccines. 0.277083333. PubMed
  154. Lee L, et al. 2016. PLoS One. 11:e0167693. PubMed
  155. Arce-Cerezo A, et al. 2015. Sci Rep. 5: 1448. PubMed
  156. Ballet R, et al. 2014. PLoS Pathog. 10:1004550. PubMed
  157. Choi EW, et al. 2020. Sci Rep. 10:12001. PubMed
  158. Denny JE, et al. 2019. Sci Rep. 2.786111111. PubMed
  159. Liu C et al. 2019. Immunity. 51(2):381-397 . PubMed
  160. Simula L et al. 2018. Cell reports. 25(11):3059-3073 . PubMed
  161. Gao C, et al. 2017. Mol Neurobiol.. 10.1007/s12035-016-0318-0. PubMed
  162. Khare P, et al. 2017. J Autoimmun. 10.1016/j.jaut.2017.09.002. PubMed
  163. Monaghan KL, et al. 2020. J Vis Exp. . PubMed
  164. Scholz F, et al. 2015. J Immunol. 195: 2335-2342. PubMed
  165. Koelwyn GJ, et al. 2020. Nat Med. 1452:26. PubMed
  166. Kim SJ, et al. 2020. Cell Mol Immunol. 17:728. PubMed
  167. Robinett RA et al. 2018. Cell systems. 7(1):41-48 . PubMed
  168. Nowlan B, et al. 2019. Haematologica. 105:71. PubMed
  169. Mohamed E, et al. 2020. Immunity. 52(4):668-682.e7.. PubMed
  170. Wuggenig P, et al. 2020. Commun Biol. 3:130. PubMed
  171. Merrell AJ, et al. 2021. Hepatology. 74:444. PubMed
  172. Chen C, et al. 2021. J Virol. 95:e0082921. PubMed
  173. Yu W, et al. 2022. Nat Commun. 13:3544. PubMed
  174. Nahrendorf W, et al. 2021. eLife. 10:00. PubMed
  175. Mansouri S, et al. 2020. Mucosal Immunol. 0.954861111. PubMed
  176. Sasaki Y, et al. 2015. PLoS One. 10: 0131176. PubMed
  177. Kalafati L, et al. 2020. Cell. 183:771. PubMed
  178. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  179. Duarte D, et al. 2018. Cell Stem Cell. 22:64. PubMed
  180. Zhang CR, et al. 2022. Blood Cancer Discov. 3:220. PubMed
  181. Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
  182. Wang S, et al. 2021. Commun Biol. 22:. PubMed
  183. Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
  184. Song J, et al. 2021. Am J Physiol Heart Circ Physiol. 320:H323. PubMed
  185. Bent EH, et al. 2021. Nat Commun. 12:6218. PubMed
  186. Calderon B, et al. 2015. J Exp Med. 212: 1497-1512. PubMed
  187. Richardson ET, et al. 2015. PLoS One. 10: 1371. PubMed
  188. Moro T, et al. 2016. PLoS One. 11: 0146592. PubMed
  189. Kobia FM, et al. 2020. PLoS Biol. 18:e3000850. PubMed
  190. Bordas M, et al. 2020. Int J Mol Sci. 21:00. PubMed
  191. Bellomo A, et al. 2020. Immunity. 53(1):127-142.e7. PubMed
  192. Jiang L, et al. 2020. Cell. 183(5):1219-1233.e18. PubMed
  193. Onai N, et al. 2020. Int J Mol Sci. :22. PubMed
  194. Celik H, et al. 2018. Cancer Cell. 34:741. PubMed
  195. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  196. Yousef H, et al. 2019. Nat Med. 25:988. PubMed
  197. Ivan DC, et al. 2021. Front Immunol. 12:666961. PubMed
  198. Franklin DA, et al. 2020. JCI Insight. 5:. PubMed
  199. Omatsu Y, et al. 2022. Nat Commun. 13:2654. PubMed
  200. Schönberger K, et al. 2022. STAR Protoc. 3:101408. PubMed
  201. Njock MS, et al. 2022. J Extracell Vesicles. 11:e12228. PubMed
  202. Bagati A, et al. 2020. Cancer Cell. 39(1):54-67.e9. PubMed
  203. Gicheva N, et al. 2016. Biochem Biophys Res Commun. 479:1-4. PubMed
  204. Beauchamp N, et al. 2010. J Virol. 84:10191. PubMed
  205. Wang Y, et al. 2020. eLife. 9:e57438.. PubMed
  206. Yu L, et al. 2020. Nat Commun. 2.045833333. PubMed
  207. McKenzie MD, et al. 2019. Cell Stem Cell. 25:258. PubMed
  208. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  209. Contreras NA, et al. 2019. PLoS Pathog. 15:e1007890. PubMed
  210. Cantor DJ et al. 2019. Cell reports. 26(1):108-118 . PubMed
  211. Baratin M, et al. 2017. Immunity. 47:349. PubMed
  212. Coley WD et al. 2018. F1000Research. 2018 Mar 14 [revised 2018 Jan 1] 0.5125. PubMed
  213. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  214. Sun L, et al. 2022. Adv Sci (Weinh). 9:e2104051. PubMed
  215. Canedo T, et al. 2021. Neuropsychopharmacology. 46:2358. PubMed
  216. Johnson RM, et al. 2021. Front Immunol. 11:614697. PubMed
  217. Kiss M, et al. 2020. Cancer Immunol Res. 9:309. PubMed
  218. Gourvest M, et al. 2021. Leukemia. . PubMed
  219. McPhee C, et al. 2013. J Immunol. 191:4581. PubMed
  220. Fujimura N, et al. 2016. Sci Rep. 5:11664. PubMed
  221. Tsunekuni K, et al. 2020. J Clin Med. 9:00. PubMed
  222. Huang WC, et al. 2020. Adv Mater. 32:e2005637. PubMed
  223. Shin M, et al. 2020. Cell Chem Biol. 314:27. PubMed
  224. Kaiser S, et al. 2020. Glia. 2427:68. PubMed
  225. Aggio-Bruce R, et al. 2020. Mol Neurobiol. . PubMed
  226. Santopaolo M, et al. 2021. Front Immunol. 609406:12. PubMed
  227. Asada S, et al. 2018. Nat Commun. 9:2733. PubMed
  228. Kong XF, et al. 2018. Nat Immunol. 19:973. PubMed
  229. Rosen DA, et al. 2019. Sci Transl Med. 11:eaau5266. PubMed
  230. Dokoshi T, et al. 2020. Cell Rep. 30:61. PubMed
  231. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 0.252777778. PubMed
  232. Süß P, et al. 2020. Cell Reports. 30(12):4082-4095. PubMed
  233. Molgora M, et al. 2020. Cell. 182:886. PubMed
  234. Shi J, et al. 2022. Front Pharmacol. 12:818326. PubMed
  235. Gao P, et al. 2020. Front Immunol. 1.636111111. PubMed
  236. Chen S, et al. 2015. Cancer Res . 7: 519-531. PubMed
  237. Groppa E, et al. 2015. EMBO Mol Med. 2015; 7: 1366 - 1384. PubMed
  238. Gharib S, et al. 2014. J Leukoc Biol. 95:9. PubMed
  239. Alfaro M, et al. 2008. Proc Natl Acad Sci U S A. 105:18366. PubMed
  240. Walker JA, et al. 2020. Immunity. 51(1):104-118. PubMed
  241. Winter C, et al. 2018. Cell Metab. 28:175. PubMed
  242. Tippimanchai DD, et al. 2018. Oncoimmunology. 7:e1438105. PubMed
  243. Liu G, et al. 2022. Theranostics. 12:2248. PubMed
  244. Fan HH, et al. 2021. Methods Mol Biol. 2276:203. PubMed
  245. Monteiro LB, et al. 2020. MethodsX. 7:100938. PubMed
  246. Rodriguez-Tirado C, et al. 2022. Cancers (Basel). 14:. PubMed
  247. Lau P, et al. 2022. Cell Mol Immunol. :. PubMed
  248. Harding CL, et al. 2020. Front Cell Infect Microbiol. 10:328. PubMed
  249. Chavez JS, et al. 2022. Cells. 11:. PubMed
  250. Boulch M, et al. 2021. Sci Immunol. 6:. PubMed
  251. Xu G, et al. 2015. Free Radic Biol Med. 87: 15-25. PubMed
  252. Zhang S, et al. 2016. PLoS Pathog. 12: 1005617. PubMed
  253. Saul S, et al. 2019. J Leukoc Biol. N/A. PubMed
  254. Severe N et al. 2019. Cell Stem Cell. 25(4):570-583 . PubMed
  255. Boguslawski KM, et al. 2020. Sci Adv. 6:eaax7515. PubMed
  256. Wang L, et al. 2020. J Nanobiotechnology. 18:38. PubMed
  257. Akhand SS, et al. 2020. Cancer Immunol Res. 8:1542. PubMed
  258. Mansouri S, et al. 2021. J Immunol. 206:2233. PubMed
  259. Franklin R, et al. 2022. Nat Commun. 13:2350. PubMed
  260. Gawish R, et al. 2022. Elife. 11:. PubMed
  261. Zhang B, et al. 2021. Front Neurol. 607370:12. PubMed
  262. Young K, et al. 2021. Cell Stem Cell. . PubMed
  263. Lucas ED, et al. 2020. Cell Reports. 33(2):108258. PubMed
  264. Zysset D, et al. 2016. Nat Commun. 7:13151. PubMed
  265. Huanga J, et al. 2013. J Immunol Methods. 387:254. PubMed
  266. Maas SLN, et al. 2020. J Neuroinflammation. 17:120. PubMed
  267. Qi S, et al. 2020. Theranostics. 10:1814. PubMed
  268. Zheng W, et al. 2019. Cell Rep. 29:1747. PubMed
  269. Lalor R, et al. 2019. Nutrients. 11. PubMed
  270. Cai T, et al. 2022. Front Immunol. 13:1009932. PubMed
  271. Scheyltjens I, et al. 2022. Nat Protoc. 17:2354. PubMed
  272. Zhang Y, et al. 2022. J Immunother Cancer. 10:. PubMed
  273. Wang Y, et al. 2022. Nat Cell Biol. 24:230. PubMed
  274. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  275. Xie Z, et al. 2020. Light Sci Appl. 9:161. PubMed
RRID
AB_312798 (BioLegend Cat. No. 101215)
AB_312799 (BioLegend Cat. No. 101216)

Antigen Details

Structure
Integrin family, associates with integrin β2 (CD18), 170 kD
Distribution

Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subsets of T and B cells

Function
Adhesion, chemotaxis
Ligand/Receptor
ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen
Cell Type
B cells, Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653.

Gene ID
16409 View all products for this Gene ID 3684 View all products for this Gene ID
UniProt
View information about CD11b on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD11b Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse/human CD11b M1/70 FC
Biotin anti-mouse/human CD11b M1/70 FC
FITC anti-mouse/human CD11b M1/70 FC
PE anti-mouse/human CD11b M1/70 FC, IHC
PE/Cyanine5 anti-mouse/human CD11b M1/70 FC
Purified anti-mouse/human CD11b M1/70 FC, CyTOF®, IP, IHC-F, ICC
PE/Cyanine7 anti-mouse/human CD11b M1/70 FC
Alexa Fluor® 488 anti-mouse/human CD11b M1/70 FC, IHC-F, 3D IHC, SB
Alexa Fluor® 647 anti-mouse/human CD11b M1/70 FC, 3D IHC
Alexa Fluor® 700 anti-mouse/human CD11b M1/70 FC
Pacific Blue™ anti-mouse/human CD11b M1/70 FC
APC/Cyanine7 anti-mouse/human CD11b M1/70 FC
PerCP/Cyanine5.5 anti-mouse/human CD11b M1/70 FC
PerCP anti-mouse/human CD11b M1/70 FC
Brilliant Violet 421™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 570™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 605™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 650™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 711™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 785™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 510™ anti-mouse/human CD11b M1/70 FC, ICC
Ultra-LEAF™ Purified anti-mouse/human CD11b M1/70 FC, CyTOF®, IP, Block, Depletion, IHC-F, ICC
Purified anti-mouse/human CD11b (Maxpar® Ready) M1/70 FC, CyTOF®
Alexa Fluor® 594 anti-mouse/human CD11b M1/70 IHC-F, FC
PE/Dazzle™ 594 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 750 anti-mouse/human CD11b M1/70 FC
TotalSeq™-A0014 anti-mouse/human CD11b M1/70 PG
Brilliant Violet 750™ anti-mouse/human CD11b M1/70 FC
TotalSeq™-B0014 anti-mouse/human CD11b M1/70 PG
TotalSeq™-C0014 anti-mouse/human CD11b M1/70 PG
Spark NIR™ 685 anti-mouse/human CD11b M1/70 FC
PE/Fire™ 640 anti-mouse/human CD11b M1/70 FC
Spark YG™ 593 anti-mouse/human CD11b M1/70 FC
Spark YG™ 570 anti-mouse/human CD11b M1/70 IHC-F
PE/Fire™ 810 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 810 anti-mouse/human CD11b Antibody M1/70 FC
Spark Blue™ 550 anti-mouse/human CD11b M1/70 FC
Spark UV™ 387 anti-mouse/human CD11b M1/70 FC
Go To Top Version: 1    Revision Date: 11.30.2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

BioLegend Inc., 8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • APC anti-mouse/human CD11b

  • Biotin anti-mouse/human CD11b

  • FITC anti-mouse/human CD11b

  • PE anti-mouse/human CD11b

  • PE/Cyanine5 anti-mouse/human CD11b

  • Purified anti-mouse/human CD11b

  • PE/Cyanine7 anti-mouse/human CD11b

  • Alexa Fluor® 488 anti-mouse/human CD11b

  • Alexa Fluor® 647 anti-mouse/human CD11b

  • Alexa Fluor® 700 anti-mouse/human CD11b

  • Pacific Blue™ anti-mouse/human CD11b

  • APC/Cyanine7 anti-mouse/human CD11b

  • PerCP/Cyanine5.5 anti-mouse/human CD11b

  • PerCP anti-mouse/human CD11b

  • Brilliant Violet 421™ anti-mouse/human CD11b

  • Brilliant Violet 570™ anti-mouse/human CD11b

  • Brilliant Violet 605™ anti-mouse/human CD11b

  • Brilliant Violet 650™ anti-mouse/human CD11b

  • Brilliant Violet 711™ anti-mouse/human CD11b

  • Brilliant Violet 785™ anti-mouse/human CD11b

  • Brilliant Violet 510™ anti-mouse/human CD11b

  • Ultra-LEAF™ Purified anti-mouse/human CD11b

  • Purified anti-mouse/human CD11b (Maxpar® Ready)

  • Alexa Fluor® 594 anti-mouse/human CD11b

  • PE/Dazzle™ 594 anti-mouse/human CD11b

  • APC/Fire™ 750 anti-mouse/human CD11b

  • TotalSeq™-A0014 anti-mouse/human CD11b

  • Brilliant Violet 750™ anti-mouse/human CD11b

  • TotalSeq™-B0014 anti-mouse/human CD11b

  • TotalSeq™-C0014 anti-mouse/human CD11b

  • Spark NIR™ 685 anti-mouse/human CD11b

  • PE/Fire™ 640 anti-mouse/human CD11b

  • Spark YG™ 593 anti-mouse/human CD11b

  • Spark YG™ 570 anti-mouse/human CD11b

  • PE/Fire™ 810 anti-mouse/human CD11b

  • APC/Fire™ 810 anti-mouse/human CD11b Antibody

  • Spark Blue™ 550 anti-mouse/human CD11b

  • Spark UV™ 387 anti-mouse/human CD11b

ProductsHere

Login / Register
Remember me
Forgot your password? Reset password?
Create an Account