Description: Development proceeds in a tightly controlled manner regulated by diverse, but intersecting signaling pathways. A growing area of research examines the role of communication between the brain and surrounding systems to regulate development and function. This video, provided by The Scientist and cosponsored by BioLegend, brings together a panel of experts to discuss the role of these synergistic interactions. Topics covered include signaling between the neural and vascular systems during development, as well as the role of cerebrospinal fluid in regulating neurogenesis.