- 7D4-6 (See other available formats)
- Regulatory Status
- Other Names
- KDR, Vascular Endothelial Receptor 2 (VEGF-R2, VEGFR2, VEGFR)
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
CD309, also known as VEGF-R2, KDR, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF-R2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, and VEGF-D splice isoforms. Activation of VEGF-R2 with its ligands results in the receptor dimerization and autophosphorylation, stimulating endothelial cell proliferation and migration.Product Details
- Verified Reactivity
- Antibody Type
- Host Species
- Human KDR recombinant protein
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
FC - Quality tested
ICC - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. For immunocytochemistry, a concentration range of 5.0 - 10 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
AB_2562485 (BioLegend Cat. No. 359902)
- Type I transmembrane glycoprotein, type III tyrosine kinase receptor, CSF-1/PDGF receptor family
Endothelial cells, embryonic tissues
- VEGF-A, VEGF-C, and VEGF-D splice isoforms
- Cell Type
- Endothelial cells
- Biology Area
- Angiogenesis, Cell Biology, Immunology
- Molecular Family
- CD Molecules
- Antigen References
1. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules: The CD Markers Wiley-Liss A John Wiley & Sons Inc, Publication.
2. Ferrara N and Gerber HP. 2002. Acta. Haematol. 106:148.
3. Murohara T, et al. 1998. Circulation. 97:99.
- Gene ID
- 3791 View all products for this Gene ID
- View information about CD309 on UniProt.org
|Purified anti-human CD309 (VEGFR2)||7D4-6||FC,ICC|
|PE anti-human CD309 (VEGFR2)||7D4-6||FC|
|PerCP/Cyanine5.5 anti-human CD309 (VEGFR2)||7D4-6||FC|
|Alexa Fluor® 647 anti-human CD309 (VEGFR2)||7D4-6||FC|
|PE/Cyanine7 anti-human CD309 (VEGFR2)||7D4-6||FC|
|Alexa Fluor® 488 anti-human CD309 (VEGFR2)||7D4-6||FC|
|APC anti-human CD309 (VEGFR2)||7D4-6||FC|
|PE/Dazzle™ 594 anti-human CD309 (VEGFR2)||7D4-6||FC|
|TotalSeq™-A0362 anti-human CD309 (VEGFR2)||7D4-6||PG|
|TotalSeq™-C0362 anti-human CD309 (VEGFR2)||7D4-6||PG|
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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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Purified anti-human CD309 (VEGFR2)
PE anti-human CD309 (VEGFR2)
PerCP/Cyanine5.5 anti-human CD309 (VEGFR2)
Alexa Fluor® 647 anti-human CD309 (VEGFR2)
PE/Cyanine7 anti-human CD309 (VEGFR2)
Alexa Fluor® 488 anti-human CD309 (VEGFR2)
APC anti-human CD309 (VEGFR2)
PE/Dazzle™ 594 anti-human CD309 (VEGFR2)
TotalSeq™-A0362 anti-human CD309 (VEGFR2)
TotalSeq™-C0362 anti-human CD309 (VEGFR2)