- 2F83 (See other available formats)
- Other Names
- Forkhead box protein A1, HNF3α, Hepatic nuclear factor 3 α
- Mouse IgG1, κ
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- Product Citations
FOXA1 is a transcriptional activator that is required for tissue-specific differentiation during embryonic development. It also functions as a coactivator with nuclear hormone receptors, including ESR1, and has been shown to play a major role in driving estrogen receptor positive breast cancers.Product Details
- Antibody Type
- Host Species
- Full length recombinant human FOXA1
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
WB - Quality tested
ICC, IHC-P - Validated
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1 - 1.0 µg per ml. For immunocytochemistry, a concentration range of 1.25 - 5.0 μg/ml is recommended. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 5.0 - 10 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
When using this clone for western blot, we highly recommend using lysate that has not been subjected to any freeze-thaw cycles.
(PubMed link indicates BioLegend citation)
- Besenard V, et al. 2004. Gene Expr Patterns. 5:193-208. (IHC-P)
- FOXA1 is a 472 amino acid protein with a predicted molecular weight of 49 kD.
Nucleus/Early endoderm derived cells
- Transcriptional activator
- FOXA2, NKX2-1, Histones H3 and H4
- Biology Area
- Cell Biology, Transcription Factors
- Molecular Family
- Nuclear Markers
- Gene ID
- 3169 View all products for this Gene ID
- View information about FOXA1 on UniProt.org
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