PE/Cyanine7 anti-human CD27, CD27, M-T271

Analyte Specific Reagent. Analytical and performance characteristics are not established.

Clone: M-T271
Workshop: V 5T CD27.03
Other Names: S152, T14, TNFRSF7
Isotype: Mouse IgG1, κ

M-T271_PECyanine7_CD27_ASR_020323 — Typical results from human peripheral blood lymphocytes stained either with M-T271 PE/Cyanine7 used at 5 µL/test (filled histogram) or with an isotype control (open histogram)

Compare all formats See PE/Cyanine7 spectral data

Cat #	Size	Price	Save
986902	500 µL	¥102,740

Description

CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70, and plays a role in costimulation of T cell activation and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.

Product Details

Technical data sheet

Product Details

Reactivity

Human

Formulation

Phosphate-buffered solution, pH7.2, containing True-Stain Monocyte Blocker™, 0.09% sodium azide, 0.2% (w/v) BSA (origin USA), and a stabilizer.

Preparation

The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.

Concentration

100 µg/mL

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

Suggested for Flow Cytometry

Disclaimer

WARNINGS AND PRECAUTIONS

Use appropriate personal protective equipment and safety practices per universal precautions when working with this reagent. Refer to the reagent safety data sheet.
This antibody contains sodium azide. Follow federal, state and local regulations to dispose of this reagent. Sodium azide build-up in metal wastepipes may lead to explosive conditions; if disposing of reagent down wastepipes, flush with water after disposal.
All specimens, samples and any material coming in contact with them should be considered potentially infectious and should be disposed of with proper precautions and in accordance with federal, state and local regulations.
Do not use this reagent beyond the expiration date stated on the label.
Do not use this reagent if it appears cloudy or if there is any change in the appearance of the reagent as these may be an indication of possible deterioration.
Avoid prolonged exposure of the reagent or stained cells to light.

Antigen Details

Antigen References

Knapp W, et al. 1989. Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press.
Schlossman S, et al. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press.
Hintzen R, et al. 1994. Immunol Today. 15:307-11.
Agematsu K, et al. 1995. J Immunol. 154:3627-35.

Documentation

Certificate of Analysis

Go To Top Version: 1 Revision Date: 02/16/2023

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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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