PE anti-human CD323 (JAM3) Antibody

Pricing & Availability
SHM33 (See other available formats)
Other Names
JAM-C, Jcam3
Mouse IgG2a, κ
Ave. Rating
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Product Citations
Human melanoma cell line, A375, was stained with CD323 (clone SHM33) PE (filled histogram) or mouse IgG2a, κ PE isotype control (open histogram).
  • SHM33_PE_CD323_Antibody_FC_011713
    Human melanoma cell line, A375, was stained with CD323 (clone SHM33) PE (filled histogram) or mouse IgG2a, κ PE isotype control (open histogram).
See PE spectral data
Cat # Size Price Save
356703 25 tests ¥23,000
356704 100 tests ¥58,000

CD323, also known as JAM3 and JAM-C, is a member of the junctional adhesion molecule family and plays a role in leukocyte migration.  It is a type I transmembrane protein and is involved in cell-cell adhesion by forming homotypic or heterotypic molecules with JAM family members or integrins.  CD323 is expressed in intestinal epithelial cells and is a component of epithelial desmosomes, endothelial cells, and platelets.  It is expressed at low levels on T cells and is upregulated upon activation.  Due to their presence in tight junction and lateral membranes, JAMs are candidate receptors for leukocytes to use when they migrate.  Thrombin induces localization of JAM3 in the tight junctions, whereas angiopoietin-1 prevents JAM3 localization.

Product Details
Technical data sheet

Product Details

Antibody Type
Host Species
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Product Citations
  1. Fielding CA et al. 2017. eLife. 6 pii: e22206. PubMed
AB_2561802 (BioLegend Cat. No. 356703)
AB_2561803 (BioLegend Cat. No. 356704)

Antigen Details

42 kD, type I transmembrane protein, immunoglobulin superfamily
Intestinal epithelial cells, epithelia desmosomes, peripheral B cells, endothelial cells, platelets and a subset of T cells
Leukocyte migration
Cell Type
Epithelial cells, B cells, Endothelial cells, Platelets, T cells
Biology Area
Cell Adhesion, Cell Biology, Immunology
Molecular Family
CD Molecules
Gene ID
83700 View all products for this Gene ID
View information about CD323 on

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 02/13/2013

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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