FITC anti-human CD61, CD61, VI-PL2

Analyte Specific Reagent. Analytical and performance characteristics are not established.

Clone: VI-PL2
Other Names: Integrin β3, gpIIIa
Isotype: Mouse IgG1, κ

VI-PL2_FITC_CD61_ASR_092923 — Typical results from human peripheral blood platelets stained either with VI-PL2 FITC used at 5 μL/test (filled histogram) or with an isotype control (open histogram).

Compare all formats See FITC spectral data

Cat #	Size	Price	Save
988002	500 µL	¥54,780

Description

CD61, also known as integrin β3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin αV (CD51) to form αV/β3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins.

Product Details

Technical data sheet

Product Details

Reactivity

Human

Formulation

Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 0.2% (w/v) BSA (origin USA), and a stabilizer.

Preparation

The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.

Concentration

100 µg/mL

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

Suggested for Flow Cytometry

Disclaimer

WARNINGS AND PRECAUTIONS

Use appropriate personal protective equipment and safety practices per universal precautions when working with this reagent. Refer to the reagent safety data sheet.
This antibody contains sodium azide. Follow federal, state and local regulations to dispose of this reagent. Sodium azide build-up in metal wastepipes may lead to explosive conditions; if disposing of reagent down wastepipes, flush with water after disposal.
All specimens, samples and any material coming in contact with them should be considered potentially infectious and should be disposed of with proper precautions and in accordance with federal, state and local regulations.
Do not use this reagent beyond the expiration date stated on the label.
Do not use this reagent if it appears cloudy or if there is any change in the appearance of the reagent as these may be an indication of possible deterioration.
Avoid prolonged exposure of the reagent or stained cells to light.

Antigen Details

Antigen References

Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules: The CD Markers.

Documentation

Certificate of Analysis

Go To Top Version: 1 Revision Date: 11/01/2023

Analyte Specific Reagent. Analytical and performance characteristic are not established.

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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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