- BA5b (See other available formats)
- Regulatory Status
- VI N-L078
- Other Names
- ADA-binding protein, DPP IV ectoenzyme, EC 188.8.131.52
- Mouse IgG2a, κ
- Ave. Rating
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- Product Citations
CD26 is a 110 kD type II membrane protein also known as ADA-binding protein and dipeptidyl peptidase IV (DPPIV). It is a member of the peptidase and ectoenzyme family. CD26 is expressed on the membrane of mature thymocytes, T lymphocytes (upregulated upon activation), B cells, NK cells, and macrophages. CD26 cleaves off N-terminal X-Pro and X-Ala dipeptides from polypeptides. It plays an integral role as a costimulatory molecule in T cell activation. CD26 may interact with extracellular matrix proteins such as fibronectin or collagen, CD45 and ADA.Product Details
- Antibody Type
- Host Species
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
(PubMed link indicates BioLegend citation)
- Kishimoto T, et al. Eds. 1997. Leucocyte Typing VI. Garland Press. London.
- Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
AB_2566754 (BioLegend Cat. No. 302718)
- Peptidases and ectoenzyme families, type II glycoprotein, 110 kD
Thymocyte subset, memory T cells, B cells, NK cells, epithelial cells, macrophages
- Dipeptidyl peptidase, T cell costimulation, HIV entry
- Adenosine-deaminase, collagen
- Cell Type
- B cells, Epithelial cells, Macrophages, NK cells, T cells, Thymocytes
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
1. Kameoka J, et al. 1993. Science 261:466.
2. Dang N, et al. 1990. J. Exp. Med. 172:649.
- Gene ID
- 1803 View all products for this Gene ID
- View information about CD26 on UniProt.org
- How many biotin molecules are per antibody structure?
- We don't routinely measure the number of biotins with our antibody products but the number of biotin molecules range from 3-6 molecules per antibody.
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