APC anti-human CD16 Antibody

Pricing & Availability

Analyte Specific Reagent. Analytical and performance characteristics are not established.

Clone
3G8
Workshop
V NK80
Other Names
FcγRIII
Isotype
Mouse IgG1, κ
3G8_APC_CD16_ASR_Antibody_051116
Typical results from human peripheral blood lymphocytes stained either with 3G8 APC used at 5 µL/test (filled histogram) or with an isotype control (open histogram).
  • 3G8_APC_CD16_ASR_Antibody_051116
    Typical results from human peripheral blood lymphocytes stained either with 3G8 APC used at 5 µL/test (filled histogram) or with an isotype control (open histogram).
See APC spectral data
Cat # Size Price Quantity Avail. Save
980104 500 µl 240€
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Description

CD16 is known as low affinity IgG receptor III (FcγRIII). It is expressed as two distinct forms (CD16a and CD16b). CD16a (FcγRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, and placental trophoblasts in humans. CD16b (FcγRIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95% homologous to that of CD16a, and it is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC).

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Human, African Green, Baboon, Capuchin Monkey, Chimpanzee, Cynomolgus, Marmoset, Pigtailed Macaque, Rhesus, Sooty Mangabey, Squirrel Monkey
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
100 µg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

Suggested for Flow Cytometry

Antigen Details

Antigen References

1. Fleit H, et al. 1982. P. Natl. Acad. Sci. USA 79:3275.
2. Stroncek D, et al. 1991. Blood 77:1572.
3. Wirthmueller U, et al. 1992. J. Exp. Med. 175:1381.

Go To Top Version: 3    Revision Date: 02/06/2018

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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