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APC anti-human CD10 Antibody

Pricing & Availability
Clone
HI10a (See other available formats)
Regulatory Status
RUO
Workshop
V CD10.7
Other Names
Common acute lymphoblastic leukemia antigen (CALLA), Enkephalinase, Neutral endopeptidase, Neprilysin
Isotype
Mouse IgG1, κ
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Product Citations
publications
HI10a
Nalm-6 cell line stained with purified HI10a and detected with anti-mouse IgGs-FITC
  • HI10a
    Nalm-6 cell line stained with purified HI10a and detected with anti-mouse IgGs-FITC
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Cat # Size Price Quantity Check Availability Save
312209 25 tests 100€
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312210 100 tests 218€
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Description

CD10 is a 100 kD neutral endopeptidase and a member of the metalloprotease family. It is a type II transmembrane protein also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin. CD10 is expressed on B cell precursors, T cell precursors, and neutrophils. CD10 is involved in B cell development and has been shown to bind opioid enkephalins, bradykinin, angiotensins I and II, and other biologically active peptides.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human, Cynomolgus, Rhesus
Reported Reactivity
African Green, Baboon, Capuchin monkey, Chimpanzee
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Red Laser (633 nm)
Product Citations
  1. Lee JK, et al. 2015. Front Cell Dev Biol. 3:13. PubMed
  2. Woo MS, et al. 2021. iScience. 24(7):102752. PubMed
  3. Gan T, et al. 2021. Cell Rep. 37:109824. PubMed
  4. Viciani E, et al. 2016. Sci Rep. 6:20609. PubMed
  5. Guo R, et al. 2020. Nat Microbiol. 0.938194444. PubMed
  6. Carlucci PM, et al. 2018. JCI Insight. 3. PubMed
  7. Xu N, et al. 2021. Cells. 10:. PubMed
  8. Dos Santos JC, et al. 2019. Cell Rep. 28:2659. PubMed
  9. Georgakis S, et al. 2021. JCI Insight. 6:. PubMed
  10. Rabold K, et al. 2022. Nat Commun. 13:6149. PubMed
  11. Dauby N, et al. 2014. J Infect Dis. 210:1275. PubMed
  12. Wang S, et al. 2021. Oncol Rep. 1.91666666666667. PubMed
  13. Wang J, et al. 2020. Cell. 183(7):1867-1883.e26. PubMed
RRID
AB_314920 (BioLegend Cat. No. 312209)
AB_314921 (BioLegend Cat. No. 312210)

Antigen Details

Structure
Type II transmembrane metalloprotease family, 100 kD
Distribution

B cell precursors, T cell precursors, neutrophils

Function
Zinc-binding metalloproteinase, B cell development
Ligand/Receptor
Biologically active peptides including opioid enkephalins, bradykinin, angiotensions I & II
Cell Type
B cells, Neutrophils
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References

1. Shipp M, et al. 1993. Blood 82:1052.
2. Lu B, et al. 1995. J. Exp. Med. 181:2271.

Gene ID
4311 View all products for this Gene ID
UniProt
View information about CD10 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 2    Revision Date: 01/17/2014

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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