- W18070C (See other available formats)
- Regulatory Status
- Other Names
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
|Cat #||Size||Price||Quantity Check Availability||Save|
CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.Product Details
- Verified Reactivity
- Antibody Type
- Host Species
- Human CD161 transfected cell line
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.
Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.
View full statement regarding label licenses
- Excitation Laser
Red Laser (633 nm)
AB_2910381 (BioLegend Cat. No. 307507)
AB_2910381 (BioLegend Cat. No. 307508)
- Type II glycoprotein, 40-44 kD homodimer, C-type lectin superfamily
NK cells, T subset, subset of CD3+ thymocytes
- LLT-1 (Lectin-like transcript-1)
- Antigen References
- Takahashi T, et al. 2006. J Immunol. 176:211-6.
- Cosmi L, et al. 2008. J Exp Med. 205:1903-16.
- Aldemir H, et al. 2005. J Immunol. 175:7791-5.
- Rosen DB, et al. 2008. J Immunol. 180:6508-17.
- Gene ID
- 3820 View all products for this Gene ID
- View information about CD161 on UniProt.org
|PE anti-human CD161||W18070C||FC|
|Purified anti-human CD161||W18070C||FC|
|Alexa Fluor® 647 anti-human CD161||W18070C||FC|
|PE/Cyanine7 anti-human CD161||W18070C||FC|
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.