PE/Cyanine7 anti-mouse/human CD11b Antibody

Pricing & Availability
Clone
M1/70 (See other available formats)
Regulatory Status
RUO
Other Names
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
M1slash70_PECy7_042706
C57BL/6 mouse bone marrow cells were stained with CD11b (clone M1/70) PE/Cyanine7 (filled histogram) or rat IgG2b, κ PE/Cyanine7 isotype control (open histogram) (gated on total cells).
  • M1slash70_PECy7_042706
    C57BL/6 mouse bone marrow cells were stained with CD11b (clone M1/70) PE/Cyanine7 (filled histogram) or rat IgG2b, κ PE/Cyanine7 isotype control (open histogram) (gated on total cells).
Compare all formats See PE/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
101215 25 µg 70€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
101216 100 µg 169€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human, Cynomolgus, Rhesus
Reported Reactivity
Chimpanzee, Baboon, Rabbit
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
C57BL/10 splenocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F).

Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1,4, in vitro blocking3,9,12, depletion2,8, immunofluorescence microscopy6,7,10, immunohistochemistry of acetone-fixed frozen sections5,11-13, and spatial biology (IBEX)35,36. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).

Additional Product Notes
BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
Application References

(PubMed link indicates BioLegend citation)
  1. Springer T, et al. 1978. Eur. J. Immunol. 8:539. (IP)
  2. Ault K and Springer T. 1981. J. Immunol. 126:359. (Deplete)
  3. Springer TA, et al. 1982. Immunol. Rev. 68:171. (Block)
  4. Ho MK and Springer TA. 1983. J. Biol. Chem. 258:2766. (IP)
  5. Flotte TJ, et al. 1983. Am. J. Pathol. 111:112. (IHC)
  6. Noel GJ, et al. 1990. J. Clin. Invest. 85:208. (IF)
  7. Allen LA and Aderem A. 1996. J. Exp. Med. 184:627 (IF)
  8. D'Amico A and Wu L. 2003. J. Exp. Med. 198:293. (Deplete)
  9. Brickson SJ, et al. 2003. Appl Physiol. 95:969. (Block)
  10. Clatworthy MR and Smith KG. 2004. J. Exp. Med. 199:717. (IF)
  11. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  12. Zhang Y, et al. 2002. J. Immunol. 168:3088. (IHC)
  13. Iwasaki A and Kelsall BL. 2001. J. Immunol. 166:4884 (IHC, FC)
  14. Tailleux L. 2003. J. Exp. Med. 197:121. (Block, FC)
  15. Olver S, et al. 2006. Cancer Research 66:571. (FC)
  16. Tan SL, et al. 2006. J. Immunol. 176:2872. (FC) PubMed
  17. Ponomarev ED, et al. 2006. J. Immunol. 176:1402. (FC)
  18. Dzhagalov I, et al. 2007. Blood 109:1620. (FC)
  19. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  20. Rasmussen JW, et al. 2006. Infect. Immun.74:6590. PubMed
  21. Napimoga MH, et al. 2008. J. Immunol. 180:609. PubMed
  22. Elqaraz-Carmon V, et al. 2008. J. Lipid. Res. 49:1894. PubMed
  23. Kim DD, et al. 2008. Blood 112:1109. PubMed
  24. Guo Y, et al. 2008. Blood 112:480. PubMed
  25. Norian LA, et al. 2009. Cancer Res. 69:3086. (FC) PubMed
  26. Baumgartner CK, et al. 2010. J. Immunol. 184:573. PubMed
  27. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  28. Whiteland J, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
  29. Weber GF, et al. 2014. J Exp Med. 211:1243. PubMed
  30. Ashok A, et al. 2015. Toxicol Sci. 143:64. PubMed
  31. Price PJ, et al. 2015. J Immunol. 194:1164. PubMed
  32. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  33. Ferreira R, et al. 2016. J Infect Dis. 213: 669 - 673. PubMed
  34. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  35. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  36. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Parsons M, et al. 2014. J Immunol. 192:1361. PubMed
  2. Tebartz C, et al. 2015. J Immunol. 194:1100. PubMed
  3. Quispe Calla N, et al. 2016. Sci Rep. 6:37723. PubMed
  4. D'Alessandro G, et al. 2020. Eur J Immunol. 50:705. PubMed
  5. DeSouza-Vieira T, et al. 2020. Cell Rep. 33:108317. PubMed
  6. Gogoi H, et al. 2020. Front Immunol. 1.620833333. PubMed
  7. Liu K, et al. 2021. Cell Metabolism. 33(3):666-675.e4. PubMed
  8. Hatzi K, et al. 2019. Nat Immunol. 20:86. PubMed
  9. Tran NT, et al. 2019. Cell Rep. 28:3510. PubMed
  10. Lin C et al. 2019. Immunity. 50(1):137-151 . PubMed
  11. Okunuki Y, et al. 2018. Proc Natl Acad Sci U S A. 115:E6264. PubMed
  12. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  13. Wang L, et al. 2021. J Nanobiotechnology. 19:56. PubMed
  14. Kuo PC, et al. 2021. Brain Commun. 3:fcab187. PubMed
  15. Rosina M, et al. 2022. Cell Metab. 34:533. PubMed
  16. Cheresh P, et al. 2021. Int J Mol Sci. 22:. PubMed
  17. Deng R, et al. 2022. Adv Sci (Weinh). 9:e2103343. PubMed
  18. Odom CV, et al. 2021. J Immunol. 207:1891. PubMed
  19. Correa S, et al. 2020. ACS Nano. 14:2224. PubMed
  20. Kim JS, et al. 2020. Immunity. 54(1):176-190.e7. PubMed
  21. Gazit R, et al. 2014. J Exp Med. 211:1315. PubMed
  22. Giorgetti E, et al. 2020. Cell Reports. 29(6):1539-1554.e7.. PubMed
  23. Thelin MA, et al. 2017. Diabetes. 66:2220. PubMed
  24. Zhang LJ, et al. 2019. Immunity. 50:121. PubMed
  25. Abels ER et al. 2019. Cell Rep. 28(12):3105-3119 . PubMed
  26. Frisbee AL, et al. 2019. Nat Commun. 10:2712. PubMed
  27. Groza D, et al. 2018. Oncoimmunology. 7:e1424676. PubMed
  28. Alissafi T, et al. 2018. J Clin Invest. 128:3840. PubMed
  29. Iwamoto H et al. 2018. Cell metabolism. 28(1):104-117 . PubMed
  30. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  31. Kitagawa S, et al. 2022. NPJ Vaccines. 7:115. PubMed
  32. Rodrigues M, et al. 2022. Biochem J. 479:1891. PubMed
  33. Jung MY, et al. 2022. Neurooncol Adv. 4:vdac017. PubMed
  34. Schönberger K, et al. 2022. Cell Stem Cell. 29:131. PubMed
  35. Di Martile M, et al. 2020. J Immunother Cancer. 8:. PubMed
  36. Sharma GP, et al. 2021. PLoS One. 16:e0259042. PubMed
  37. Li Z, et al. 2021. Immunology. 163:105. PubMed
  38. Radovanovic I, et al. 2014. J Immunol. 193:1290. PubMed
  39. Zasłona Z, et al. 2014. J Immunol. 193:4245. PubMed
  40. Zheng W, et al. 2021. Wellcome Open Research. 6:52. PubMed
  41. Mogilenko DA, et al. 2020. Immunity. 54(1):99-115.e12. PubMed
  42. Riether C, et al. 2021. Cell Reports. 34(4):108663. PubMed
  43. Yu K, et al. 2021. Cell Reports. 35(12):109273. PubMed
  44. Kurelac I, et al. 2019. Nat Commun. 10:903. PubMed
  45. Kobayashi Y, et al. 2018. PLoS One. 13:e0195008. PubMed
  46. Delás MJ, et al. 2019. Cell Rep. 27:719. PubMed
  47. Wei H, et al. 2021. Malar J. 20:89. PubMed
  48. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 5:64. PubMed
  49. Hickey A, et al. 2021. Front Microbiol. 12:653587. PubMed
  50. Morgan PK, et al. 2021. J Biol Chem. 297:101341. PubMed
  51. Yang C, et al. 2021. J Immunother Cancer. 9:. PubMed
  52. Piepke M, et al. 2021. J Neuroinflammation. 18:265. PubMed
  53. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  54. Chen T, et al. 2021. JCI Insight. 6:. PubMed
  55. Shen H, et al. 2015. Infect Immun . 83: 2694 - 2704. PubMed
  56. Periasamy S, et al. 2017. Nat Commun. 8:15564. PubMed
  57. Saggu G, et al. 2018. Nat Commun. 9:5058. PubMed
  58. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  59. Bowers E, et al. 2018. Nat Med. 24:95. PubMed
  60. Yang X, et al. 2020. Blood Sci. 2:89. PubMed
  61. Deslyper G, et al. 2021. Parasitology. 148:539. PubMed
  62. Martin R, et al. 2014. J Leukoc Biol. 96:151. PubMed
  63. Shemer A, et al. 2020. Immunity. 53(5):1033-1049.e7. PubMed
  64. Yamamoto K, et al. 2021. Cell Reports. 36(8):109576. PubMed
  65. Uroda T, et al. 2020. Nat Protoc. 15:2107. PubMed
  66. Akhmetzyanova ER, et al. 2019. Front Cell Neurosci. 12:507. PubMed
  67. Lubkin A et al. 2019. Cell host & microbe. 25(3):463-470 . PubMed
  68. Gibson EM, et al. 2019. Cell. 176:43:00. PubMed
  69. Juttukonda LJ, et al. 2017. Cell Host Microbe. 22:531. PubMed
  70. LaFleur MW, et al. 2019. Nat Immunol. 20:1335. PubMed
  71. Somerville TD, et al. 2020. eLife. 9:e53381.. PubMed
  72. Go DM, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:715. PubMed
  73. Park JA, et al. 2021. J Hematol Oncol. 14:142. PubMed
  74. Zong L, et al. 2021. NPJ Aging Mech Dis. 7:25. PubMed
  75. Almutairi F, et al. 2021. Front Immunol. 12:772288. PubMed
  76. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  77. Royzman D, et al. 2022. Front Immunol. 13:1012647. PubMed
  78. Ellis G, et al. 2015. EMBO Rep. 16: 1203-1218. PubMed
  79. Vazquez S, et al. 2015. Exp Hematol. 43: 578-585. PubMed
  80. Shade K, et al. 2015. J Exp Med. 212:457. PubMed
  81. Sasaki K, et al. 2019. Nat Commun. 10:3878. PubMed
  82. Angelidis I, et al. 2019. Nat Commun. 10:963. PubMed
  83. Xu X, et al. 2021. J Nanobiotechnology. 19:376. PubMed
  84. Walker FC, et al. 2021. PLoS Pathog. 17:e1009402. PubMed
  85. Johansen AZ, et al. 2022. Pharmaceutics. 14:. PubMed
  86. Liu Y, et al. 2022. Nat Commun. 13:2665. PubMed
  87. Beauchamp EM, et al. 2021. Blood Cancer Discov. 6:. PubMed
  88. Dodagatta-Marri E, et al. 2021. Cell Rep. 36:109309. PubMed
  89. Super M, et al. 2021. Nat Biomed Eng. Online ahead of print. PubMed
  90. Kulkarni NN, et al. 2021. J Biol Chem. 297:100828. PubMed
  91. Jia X, et al. 2021. Front Cell Dev Biol. 9:685522. PubMed
  92. Klopfenstein N, et al. 2021. PLoS Pathog. 17:e1009387. PubMed
  93. Koh F, et al. 2015. Proc Natl Acad Sci U S A. 112:1734. PubMed
  94. Kohn M, et al. 2021. Front Immunol. 580594:12. PubMed
  95. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  96. Vasilijevic J, et al. 2017. PLoS Pathog. 13:e1006650. PubMed
  97. Meeks K, et al. 2009. J Immunol. 183:8026. PubMed
  98. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  99. Wang L, et al. 2021. Cancer Immunol Res. 9:348. PubMed
  100. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  101. Shin JE, et al. 2021. Heliyon. 7:e08433. PubMed
  102. Aegerter H, et al. 2020. Nat Immunol. 0.975694444. PubMed
  103. Zhang S, et al. 2020. Front Immunol. 1.757638889. PubMed
  104. Kirschbaum K, et al. 2016. Proc Natl Acad Sci U S A. 113: 13227 - 13232. PubMed
  105. Varol D et al. 2017. Immunity. 46(6):1030-1044 . PubMed
  106. Snell LM, et al. 2018. Immunity. 49:678. PubMed
  107. Amo-Aparicio J, et al. 2021. Theranostics. 11:9805. PubMed
  108. Mansouri S, et al. 2021. J Immunol. 206:2233. PubMed
  109. Goldman E, et al. 2021. Cells. 10:. PubMed
  110. Dokoshi T, et al. 2021. J Clin Invest. 131:. PubMed
  111. Pan YC, et al. 2021. Mol Ther Oncolytics. 20:175. PubMed
  112. Xie Z, et al. 2020. Light Sci Appl. 0.486805556. PubMed
  113. Gomzikova MO, et al. 2020. Sci Rep. 10:10740. PubMed
  114. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  115. Okubo K, et al. 2021. Cell Reports. 35(7):109142. PubMed
  116. Gozgit JM, et al. 2021. Cancer Cell. :. PubMed
  117. Kooreman NG et al. 2018. Cell stem cell. 22(4):501-513 . PubMed
  118. Proto JD et al. 2018. Immunity. 49(4):666-677 . PubMed
  119. Secondini C, et al. 2017. Oncoimmunology. 6:e1316437. PubMed
  120. Huang YL, et al. 2021. Commun Biol. 4:229. PubMed
  121. Littwitz-Salomon E, et al. 2021. Nat Commun. 12:5376. PubMed
  122. Synn CB, et al. 2022. Clin Transl Immunology. 11:e1364. PubMed
  123. Jia Q, et al. 2021. Theranostics. 4699:11. PubMed
  124. Dobosz E, et al. 2021. Dis Model Mech. :14. PubMed
  125. Mulas F, et al. 2020. Cell Mol Immunol. . PubMed
  126. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  127. Bambouskova M, et al. 2021. Cell Reports. 34(10):108756. PubMed
  128. Ringel AE, et al. 2020. Cell. 183(7):1848-1866.e26. PubMed
  129. Pérez-Girón J, et al. 2015. J Vis Exp. 100: 52803. PubMed
  130. Suresh MV, et al. 2019. JCI Insight. 4:e133103. PubMed
  131. Patel S, et al. 2019. Viruses. 0.877083333. PubMed
  132. Bradley KC, et al. 2019. Cell Rep. 28:245. PubMed
  133. Kumar MP, et al. 2018. Cell Rep. 25:1458. PubMed
  134. Steuerman Y et al. 2018. Cell systems. 6(6):679-691 . PubMed
  135. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  136. Uddin MJ, et al. 2022. Mucosal Immunol. 15:165. PubMed
  137. Wang D, et al. 2021. Nat Commun. 12:2674. PubMed
  138. Boulay A, et al. 2015. J Neurosci. 35:4427. PubMed
  139. Trefzer A, et al. 2021. Cell Reports. 34(6):108748. PubMed
  140. Lim CX, et al. 2020. Cell Rep. 3793:30. PubMed
  141. Li Z, et al. 2018. Front Immunol. 9:347. PubMed
  142. Marcus A et al. 2018. Immunity. 49(4):754-763 . PubMed
  143. Van Winkle JA et al. 2018. Cell host & microbe. 24(5):665-676 . PubMed
  144. LaFleur MW, et al. 2019. Nat Commun. 10:1668. PubMed
  145. Wilson DH, et al. 2020. Nat Commun. 0.767361111. PubMed
  146. Tran NT, et al. 2020. STAR Protocols. 1(1):100028. PubMed
  147. Endoh M, et al. 2020. Cell Reports. 30(6):1823-1834. PubMed
  148. Li H, et al. 2020. Nature. 584:274. PubMed
  149. Sibilio A, et al. 2022. iScience. 25:103790. PubMed
  150. Dey S, et al. 2020. J Immunother Cancer. 8:. PubMed
  151. Shen M, et al. 2022. Nat Cancer. 3:60. PubMed
  152. Liu H, et al. 2022. Front Pharmacol. 13:949316. PubMed
  153. Monaghan KL, et al. 2020. J Vis Exp. . PubMed
  154. Frenis K, et al. 2021. Basic Res Cardiol. 31:116. PubMed
  155. Crouse B, et al. 2020. NPJ Vaccines. 0.277083333. PubMed
  156. Lee L, et al. 2016. PLoS One. 11:e0167693. PubMed
  157. Arce-Cerezo A, et al. 2015. Sci Rep. 5: 1448. PubMed
  158. Ballet R, et al. 2014. PLoS Pathog. 10:1004550. PubMed
  159. Choi EW, et al. 2020. Sci Rep. 10:12001. PubMed
  160. Denny JE, et al. 2019. Sci Rep. 2.786111111. PubMed
  161. Liu C et al. 2019. Immunity. 51(2):381-397 . PubMed
  162. Simula L et al. 2018. Cell reports. 25(11):3059-3073 . PubMed
  163. Gao C, et al. 2017. Mol Neurobiol.. 10.1007/s12035-016-0318-0. PubMed
  164. Khare P, et al. 2017. J Autoimmun. 10.1016/j.jaut.2017.09.002. PubMed
  165. Scholz F, et al. 2015. J Immunol. 195: 2335-2342. PubMed
  166. Koelwyn GJ, et al. 2020. Nat Med. 1452:26. PubMed
  167. Kim SJ, et al. 2020. Cell Mol Immunol. 17:728. PubMed
  168. Robinett RA et al. 2018. Cell systems. 7(1):41-48 . PubMed
  169. Nowlan B, et al. 2019. Haematologica. 105:71. PubMed
  170. Mohamed E, et al. 2020. Immunity. 52(4):668-682.e7.. PubMed
  171. Wuggenig P, et al. 2020. Commun Biol. 3:130. PubMed
  172. Merrell AJ, et al. 2021. Hepatology. 74:444. PubMed
  173. Chen C, et al. 2021. J Virol. 95:e0082921. PubMed
  174. Yu W, et al. 2022. Nat Commun. 13:3544. PubMed
  175. Nahrendorf W, et al. 2021. eLife. 10:00. PubMed
  176. Mansouri S, et al. 2020. Mucosal Immunol. 0.954861111. PubMed
  177. Sasaki Y, et al. 2015. PLoS One. 10: 0131176. PubMed
  178. Kalafati L, et al. 2020. Cell. 183:771. PubMed
  179. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  180. Duarte D, et al. 2018. Cell Stem Cell. 22:64. PubMed
  181. Zhang CR, et al. 2022. Blood Cancer Discov. 3:220. PubMed
  182. Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
  183. Wang S, et al. 2021. Commun Biol. 22:. PubMed
  184. Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
  185. Song J, et al. 2021. Am J Physiol Heart Circ Physiol. 320:H323. PubMed
  186. Bent EH, et al. 2021. Nat Commun. 12:6218. PubMed
  187. Calderon B, et al. 2015. J Exp Med. 212: 1497-1512. PubMed
  188. Richardson ET, et al. 2015. PLoS One. 10: 1371. PubMed
  189. Moro T, et al. 2016. PLoS One. 11: 0146592. PubMed
  190. Kobia FM, et al. 2020. PLoS Biol. 18:e3000850. PubMed
  191. Bordas M, et al. 2020. Int J Mol Sci. 21:00. PubMed
  192. Bellomo A, et al. 2020. Immunity. 53(1):127-142.e7. PubMed
  193. Jiang L, et al. 2020. Cell. 183(5):1219-1233.e18. PubMed
  194. Onai N, et al. 2020. Int J Mol Sci. :22. PubMed
  195. Celik H, et al. 2018. Cancer Cell. 34:741. PubMed
  196. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  197. Yousef H, et al. 2019. Nat Med. 25:988. PubMed
  198. Ivan DC, et al. 2021. Front Immunol. 12:666961. PubMed
  199. Franklin DA, et al. 2020. JCI Insight. 5:. PubMed
  200. Omatsu Y, et al. 2022. Nat Commun. 13:2654. PubMed
  201. Liu W, et al. 2022. J Clin Invest. 132: . PubMed
  202. Schönberger K, et al. 2022. STAR Protoc. 3:101408. PubMed
  203. Njock MS, et al. 2022. J Extracell Vesicles. 11:e12228. PubMed
  204. Bagati A, et al. 2020. Cancer Cell. 39(1):54-67.e9. PubMed
  205. Gicheva N, et al. 2016. Biochem Biophys Res Commun. 479:1-4. PubMed
  206. Beauchamp N, et al. 2010. J Virol. 84:10191. PubMed
  207. Wang Y, et al. 2020. eLife. 9:e57438.. PubMed
  208. Yu L, et al. 2020. Nat Commun. 2.045833333. PubMed
  209. McKenzie MD, et al. 2019. Cell Stem Cell. 25:258. PubMed
  210. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  211. Contreras NA, et al. 2019. PLoS Pathog. 15:e1007890. PubMed
  212. Cantor DJ et al. 2019. Cell reports. 26(1):108-118 . PubMed
  213. Baratin M, et al. 2017. Immunity. 47:349. PubMed
  214. Coley WD et al. 2018. F1000Research. 2018 Mar 14 [revised 2018 Jan 1] 0.5125. PubMed
  215. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  216. Sadhu S, et al. 2021. J Immunol. 207:1812. PubMed
  217. Sun L, et al. 2022. Adv Sci (Weinh). 9:e2104051. PubMed
  218. Canedo T, et al. 2021. Neuropsychopharmacology. 46:2358. PubMed
  219. Johnson RM, et al. 2021. Front Immunol. 11:614697. PubMed
  220. Kiss M, et al. 2020. Cancer Immunol Res. 9:309. PubMed
  221. Gourvest M, et al. 2021. Leukemia. . PubMed
  222. McPhee C, et al. 2013. J Immunol. 191:4581. PubMed
  223. Fujimura N, et al. 2016. Sci Rep. 5:11664. PubMed
  224. Tsunekuni K, et al. 2020. J Clin Med. 9:00. PubMed
  225. Huang WC, et al. 2020. Adv Mater. 32:e2005637. PubMed
  226. Shin M, et al. 2020. Cell Chem Biol. 314:27. PubMed
  227. Kaiser S, et al. 2020. Glia. 68:2427. PubMed
  228. Aggio-Bruce R, et al. 2020. Mol Neurobiol. . PubMed
  229. Santopaolo M, et al. 2021. Front Immunol. 609406:12. PubMed
  230. Molgora M, et al. 2020. Cell. 182:886. PubMed
  231. Asada S, et al. 2018. Nat Commun. 9:2733. PubMed
  232. Kong XF, et al. 2018. Nat Immunol. 19:973. PubMed
  233. Rosen DA, et al. 2019. Sci Transl Med. 11:eaau5266. PubMed
  234. Dokoshi T, et al. 2020. Cell Rep. 30:61. PubMed
  235. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 0.252777778. PubMed
  236. Süß P, et al. 2020. Cell Reports. 30(12):4082-4095. PubMed
  237. Shi J, et al. 2022. Front Pharmacol. 12:818326. PubMed
  238. Gao P, et al. 2020. Front Immunol. 1.636111111. PubMed
  239. Chen S, et al. 2015. Cancer Res . 7: 519-531. PubMed
  240. Groppa E, et al. 2015. EMBO Mol Med. 2015; 7: 1366 - 1384. PubMed
  241. Gharib S, et al. 2014. J Leukoc Biol. 95:9. PubMed
  242. Alfaro M, et al. 2008. Proc Natl Acad Sci U S A. 105:18366. PubMed
  243. Walker JA, et al. 2020. Immunity. 51(1):104-118. PubMed
  244. Winter C, et al. 2018. Cell Metab. 28:175. PubMed
  245. Tippimanchai DD, et al. 2018. Oncoimmunology. 7:e1438105. PubMed
  246. Liu G, et al. 2022. Theranostics. 12:2248. PubMed
  247. Fan HH, et al. 2021. Methods Mol Biol. 2276:203. PubMed
  248. Monteiro LB, et al. 2020. MethodsX. 7:100938. PubMed
  249. Rodriguez-Tirado C, et al. 2022. Cancers (Basel). 14:. PubMed
  250. Lau P, et al. 2022. Cell Mol Immunol. :. PubMed
  251. Harding CL, et al. 2020. Front Cell Infect Microbiol. 10:328. PubMed
  252. Chavez JS, et al. 2022. Cells. 11:. PubMed
  253. Boulch M, et al. 2021. Sci Immunol. 6:. PubMed
  254. Xu G, et al. 2015. Free Radic Biol Med. 87: 15-25. PubMed
  255. Zhang S, et al. 2016. PLoS Pathog. 12: 1005617. PubMed
  256. Saul S, et al. 2019. J Leukoc Biol. N/A. PubMed
  257. Severe N et al. 2019. Cell Stem Cell. 25(4):570-583 . PubMed
  258. Boguslawski KM, et al. 2020. Sci Adv. 6:eaax7515. PubMed
  259. Wang L, et al. 2020. J Nanobiotechnology. 18:38. PubMed
  260. Mansouri S, et al. 2021. J Immunol. 206:2233. PubMed
  261. Franklin R, et al. 2022. Nat Commun. 13:2350. PubMed
  262. Gawish R, et al. 2022. Elife. 11:. PubMed
  263. Akhand SS, et al. 2020. Cancer Immunol Res. 8:1542. PubMed
  264. Zhang B, et al. 2021. Front Neurol. 607370:12. PubMed
  265. Young K, et al. 2021. Cell Stem Cell. . PubMed
  266. Lucas ED, et al. 2020. Cell Reports. 33(2):108258. PubMed
  267. Zysset D, et al. 2016. Nat Commun. 7:13151. PubMed
  268. Huanga J, et al. 2013. J Immunol Methods. 387:254. PubMed
  269. Maas SLN, et al. 2020. J Neuroinflammation. 17:120. PubMed
  270. Qi S, et al. 2020. Theranostics. 10:1814. PubMed
  271. Zheng W, et al. 2019. Cell Rep. 29:1747. PubMed
  272. Lalor R, et al. 2019. Nutrients. 11. PubMed
  273. Cai T, et al. 2022. Front Immunol. 13:1009932. PubMed
  274. Scheyltjens I, et al. 2022. Nat Protoc. 17:2354. PubMed
  275. Zhang Y, et al. 2022. J Immunother Cancer. 10:. PubMed
  276. Wang Y, et al. 2022. Nat Cell Biol. 24:230. PubMed
  277. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  278. Xie Z, et al. 2020. Light Sci Appl. 9:161. PubMed
RRID
AB_312798 (BioLegend Cat. No. 101215)
AB_312799 (BioLegend Cat. No. 101216)

Antigen Details

Structure
Integrin family, associates with integrin β2 (CD18), 170 kD
Distribution

Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subsets of T and B cells

Function
Adhesion, chemotaxis
Ligand/Receptor
ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen
Cell Type
B cells, Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653.

Gene ID
16409 View all products for this Gene ID 3684 View all products for this Gene ID
UniProt
View information about CD11b on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD11b Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse/human CD11b M1/70 FC
Biotin anti-mouse/human CD11b M1/70 FC
FITC anti-mouse/human CD11b M1/70 FC
PE anti-mouse/human CD11b M1/70 FC,IHC
PE/Cyanine5 anti-mouse/human CD11b M1/70 FC
Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,IHC-F,ICC
PE/Cyanine7 anti-mouse/human CD11b M1/70 FC
Alexa Fluor® 488 anti-mouse/human CD11b M1/70 FC,IHC-F,3D IHC,SB
Alexa Fluor® 647 anti-mouse/human CD11b M1/70 FC,3D IHC,SB
Alexa Fluor® 700 anti-mouse/human CD11b M1/70 FC
Pacific Blue™ anti-mouse/human CD11b M1/70 FC
APC/Cyanine7 anti-mouse/human CD11b M1/70 FC
PerCP/Cyanine5.5 anti-mouse/human CD11b M1/70 FC
PerCP anti-mouse/human CD11b M1/70 FC
Brilliant Violet 421™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 570™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 605™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 650™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 711™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 785™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 510™ anti-mouse/human CD11b M1/70 FC,ICC
Ultra-LEAF™ Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,Block,Depletion,IHC-F,ICC
Purified anti-mouse/human CD11b (Maxpar® Ready) M1/70 FC,CyTOF®
Alexa Fluor® 594 anti-mouse/human CD11b M1/70 IHC-F,FC
PE/Dazzle™ 594 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 750 anti-mouse/human CD11b M1/70 FC
TotalSeq™-A0014 anti-mouse/human CD11b M1/70 PG
Brilliant Violet 750™ anti-mouse/human CD11b M1/70 FC
TotalSeq™-B0014 anti-mouse/human CD11b M1/70 PG
TotalSeq™-C0014 anti-mouse/human CD11b M1/70 PG
Spark NIR™ 685 anti-mouse/human CD11b M1/70 FC
PE/Fire™ 640 anti-mouse/human CD11b M1/70 FC
Spark YG™ 593 anti-mouse/human CD11b M1/70 FC
Spark YG™ 570 anti-mouse/human CD11b M1/70 IHC-F
PE/Fire™ 810 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 810 anti-mouse/human CD11b Antibody M1/70 FC
Spark Blue™ 550 anti-mouse/human CD11b M1/70 FC
Spark UV™ 387 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 806 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 780 anti-mouse/human CD11b M1/70 FC
Spark Blue™ 574 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
KIRAVIA Blue 520™ anti-mouse/human CD11b M1/70 FC
Spark PLUS UV™ 395 anti-mouse/human CD11b M1/70 FC
Go To Top Version: 1    Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere

Login / Register
Remember me
Forgot your password? Reset password?
Create an Account