Loading...

Biotin anti-human CD303 (BDCA-2) Antibody

Pricing & Availability
Clone
201A (See other available formats)
Regulatory Status
RUO
Other Names
CLEC4C, CLECSF11, CLECSF7, DLEC, HECL
Isotype
Mouse IgG2a, κ
Ave. Rating
Submit a Review
Product Citations
publications
201A_Biotin_CD303_Antibody_1_032316
Human peripheral mononuclear cells were stained with CD123 APC and biotinylated CD303 (clone 201A) (top), or biotinylated mouse IgG2a, κ isotype control (bottom), followed by SAV-PE. Data shown was gated on the lymphocyte and monocyte populations.
  • 201A_Biotin_CD303_Antibody_1_032316
    Human peripheral mononuclear cells were stained with CD123 APC and biotinylated CD303 (clone 201A) (top), or biotinylated mouse IgG2a, κ isotype control (bottom), followed by SAV-PE. Data shown was gated on the lymphocyte and monocyte populations.
  • 201A_Biotin_CD303_Antibody_2_032316
Compare all formats
Cat # Size Price Quantity Check Availability Save
354220 100 µg 212€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD303, also known as BDCA-2 and CLEC4C, is a 38 kD type II transmembrane glycoprotein. It is a member of the C-type lectin superfamily. CD303 is expressed by plasmacytoid dendritic cells (pDCs) and is involved in cell adhesion, signaling, and antigen capture and processing. Crosslinking of CD303 inhibits the production of IFN-α/β and TLR-9 induced pDCs maturation.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Freeman A, et al. 2014. PLoS One. 9:110928. PubMed
  2. Johnson P, et al. 2015. Clin Cnacer Res. 21:1321. PubMed
RRID
AB_2572077 (BioLegend Cat. No. 354220)

Antigen Details

Structure
Type II transmembrane protein, 38 kD, member of the C-type lectin superfamily
Distribution

Plasmacytoid dendritic cells

Function
Antigen capture, inhibition of IFN α/β production
Cell Type
Dendritic cells
Biology Area
Costimulatory Molecules, Immunology, Innate Immunity
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Jähn PS, et al. 2010. Cell Immunol. 265:15.
2. Graham LM and Brown GD. 2009. Cytokine 48:148.
3. Röck J, et al. 2007. Eur. J. Immunol. 37:3564.
4. Dzionek A, et al. 2001. J. Exp. Med. 194:1823.

Gene ID
170482 View all products for this Gene ID
UniProt
View information about CD303 on UniProt.org

Related FAQs

How many biotin molecules are per antibody structure?
We don't routinely measure the number of biotins with our antibody products but the number of biotin molecules range from 3-6 molecules per antibody.
Go To Top Version: 1    Revision Date: 03/24/2016

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • APC anti-human CD303 (BDCA-2)

  • Purified anti-human CD303 (BDCA-2)

  • PE anti-human CD303 (BDCA-2)

  • FITC anti-human CD303 (BDCA-2)

  • PerCP/Cyanine5.5 anti-human CD303 (BDCA-2)

  • Brilliant Violet 421™ anti-human CD303 (BDCA-2)

  • PE/Cyanine7 anti-human CD303 (BDCA-2)

  • Purified anti-human CD303 (BDCA-2) (Maxpar® Ready)

  • Alexa Fluor® 647 anti-human CD303 (BDCA-2)

  • Biotin anti-human CD303 (BDCA-2)

  • Brilliant Violet 785™ anti-human CD303 (BDCA-2)

  • Brilliant Violet 605™ anti-human CD303 (BDCA-2)

  • PE/Dazzle™ 594 anti-human CD303 (BDCA-2)

  • Alexa Fluor® 700 anti-human CD303 (BDCA-2)

  • Alexa Fluor® 488 anti-human CD303 (BDCA-2)

  • Brilliant Violet 510™ anti-human CD303 (BDCA-2)

  • Brilliant Violet 711™ anti-human CD303 (BDCA-2)

  • APC/Fire™ 750 anti-human CD303 (BDCA-2)

  • APC/Cyanine7 anti-human CD303 (BDCA-2)

  • TotalSeq™-A0370 anti-human CD303 (BDCA-2)

  • TotalSeq™-C0370 anti-human CD303 (BDCA-2)

  • TotalSeq™-B0370 anti-human CD303 (BDCA-2)

  • TotalSeq™-D0370 anti-human CD303 (BDCA-2)

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account