Loading...

APC anti-human Podoplanin Antibody

Pricing & Availability
Clone
NC-08 (See other available formats)
Regulatory Status
RUO
Other Names
T1a, T1a2, gp36, gp38, gp40, Aggrus, PDPN, D2-40
Isotype
Rat IgG2a, λ
Ave. Rating
Submit a Review
Product Citations
publications
NC-08_APC_Podoplanin_Antibody_081318
Human glioblastoma cell line LN319 was stained with podoplanin (clone NC-08) APC (filled histogram) or Rat IgG2a, λ APC isotype control (open histogram).
  • NC-08_APC_Podoplanin_Antibody_081318
    Human glioblastoma cell line LN319 was stained with podoplanin (clone NC-08) APC (filled histogram) or Rat IgG2a, λ APC isotype control (open histogram).
Compare all formats See APC spectral data
Cat # Size Price Quantity Check Availability Save
337021 25 tests 124€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
337022 100 tests 252€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

Podoplanin is a 40-43 kD type-I transmembrane sialomucin-type glycoprotein, also known as T1a, gp36, gp38, gp40, and Aggrus. Originally detected on the surface of podocytes, futher characterization showed podoplanin has a broad tissue distribution, including mesothelial cells, epithelial cells, follicular dendritic cells, and a variety of tumor cells. It has been reported that podoplanin is the ligand of CLEC2 and is involved in lymphatic vessel formation, platelet aggregation, and tumor metastasis. Podoplanin may serve as a useful marker for tumor diagnosis and prognosis.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Rat
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunofluorescence1.

Application References

(PubMed link indicates BioLegend citation)
  1. Fujino N, et al. 2012. Am. J. Respir. Cell. Mol. Biol. 46:422. (FC, IF)
RRID
AB_2750281 (BioLegend Cat. No. 337021)
AB_2750282 (BioLegend Cat. No. 337022)

Antigen Details

Structure
40-43 kD type-I transmembrane sialomucin-type glycoprotein
Distribution

Broad tissue distribution, including mesothelial cells, epithelial cells, follicular dendritic cells, and many tumor cells

Function
Lymphatic vessel formation, tumor metastasis, platelet aggregation
Ligand/Receptor
CLEC2
Cell Type
Dendritic cells
Biology Area
Cancer Biomarkers, Cell Biology, Immunology, Neuroinflammation, Neuroscience, Neuroscience Cell Markers
Antigen References

1. Raica M, et al. 2008. Anticancer Res. 28:2997.
2. Xie Q, et al. 2008. Int. J. Clin. Exp. Pathol. 1:276.
3. Ogasawara S, et al. 2008. Hybridoma. 27:259.
4. Kato Y, et al. 2003. J. Bio. Chem. 278:51599.

Gene ID
10630 View all products for this Gene ID
UniProt
View information about Podoplanin on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 08/14/2018

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • Purified anti-human Podoplanin

  • PE anti-human Podoplanin

  • Alexa Fluor® 647 anti-human Podoplanin

  • Alexa Fluor® 488 anti-human Podoplanin

  • PE/Cyanine7 anti-human Podoplanin

  • Biotin anti-human Podoplanin

  • PerCP/Cyanine5.5 anti-human Podoplanin

  • Alexa Fluor® 594 anti-human Podoplanin

  • TotalSeq™-A0127 anti-human Podoplanin

  • APC/Cyanine7 anti-human Podoplanin

  • APC/Fire™ 750 anti-human Podoplanin

  • FITC anti-human Podoplanin

  • APC anti-human Podoplanin

  • PE/Dazzle™ 594 anti-human Podoplanin

  • TotalSeq™-C0127 anti-human Podoplanin

  • TotalSeq™-B0127 anti-human Podoplanin

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account