Purified anti-mouse CD155 (PVR) Antibody

Pricing & Availability
4.24.1 (See other available formats)
Regulatory Status
Other Names
PVR (poliovirus receptor) homolog
Rat IgG2a, κ
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Product Citations
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132202 100 µg 184€
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Mouse CD155, also known as homolog of polivirus receptor, is the founding member of a subfamily of immunoglobulin-like adhesion receptors (nectins). Mouse CD155 is expressed on a wide variety of cells of hematopoietic origin apart from its existence on the epithelial cells. The engagement of CD155 with CD226 and CD96 induces cytotoxicity of NK cells and CTL.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
EL4 transfected with mouse CD155
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References
  1. Tahara-Hanaoka S, et al. 2004. Int Immunol 16:533
  2. Maier MK, et al. 2007. Eur J. Immunol. 37:2214
  3. Bottino C, et al. 2003. J. Exp. Med. 198:557
  4. Chan CJ, et al. 2010. J. Immunol. 184;902. PubMed
Product Citations
  1. Fearnley GW, et al. 2019. Biol Open. 8:5. PubMed
AB_1279111 (BioLegend Cat. No. 132202)

Antigen Details

70 kd immunoglobulin-like molecule with three Ig-like domains.

CD155 is expressed at cell junctions on the primary vascular endothelial cells. Moreover, mouse CD155 is highly expressed on DP thymocytes and expression level is dropped in peripheral single positive CD4+ and CD8+ T cells. CD155 can be detected on T reg, other activated T cells and on NKT cells. Resident monocytes express moderate amount of CD155, but upregulated its expression during inflammation. Other cells, such as IEL, neutrophils and subsets of B cells were found to express CD155 to varying extents.

Apart from its function of adhering junction among contacting epithelial cells, the interaction of DNAM-1 (CD226) with its ligands CD155 and CD112 (nectin 2) induces cytotoxcity of NK cells and CD8+ T cells and cytokine secretion.
CD226 (DNAM-1), CD96
Cell Type
B cells, Monocytes, Neutrophils, T cells, Thymocytes, Tregs
Biology Area
Immunology, Innate Immunity
Molecular Family
Adhesion Molecules, CD Molecules, Immune Checkpoint Receptors
Antigen References

1. Mendelsohn C et al. 1989. Cell 56:855

Gene ID
52118 View all products for this Gene ID
View information about CD155 on UniProt.org

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Go To Top Version: 2    Revision Date: 07/28/2020

For Research Use Only. Not for diagnostic or therapeutic use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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