- W18349C (See other available formats)
- Regulatory Status
- Other Names
- Rat IgG2a, κ
- Ave. Rating
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- Product Citations
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CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcRI. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and mast cells. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).Product Details
- Antibody Type
- Host Species
- Recombinant mouse FcƳRI/CD64 (aa 25-297)
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- The antibody was purified by affinity chromatography.
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
AB_2894639 (BioLegend Cat. No. 164402)
- Ig superfamily, type I glycoprotein, 72 kD
Monocytes, macrophages, mast cells, dendritic cells
- Phagocytosis, ADCC
- Cell Type
- Dendritic cells, Macrophages, Mast cells, Monocytes
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, Fc Receptors
- Antigen References
- Tan PS, et al. 2003. J Immunol. 170:2549. (IP)
- Ingersoll MA, et al. 2010. Blood. 115:e10. (FC)
- Ozeri E, et al. 2012. J Immunol. 189:146.
- Richardson ML, et al. 2014. PLoS Negl Trop Dis. 8:2825.
- Gene ID
- 14129 View all products for this Gene ID
- View information about CD64 on UniProt.org
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