GMP PE anti-human CD2 Antibody

Pricing & Availability
Clone
TS1/8 (See other available formats)
Workshop
V S025
Other Names
LFA-2, T11, SRBC-R
Isotype
Mouse IgG1, κ
Ave. Rating
Submit a Review
Product Citations
publications
TS18_GMP_PE_CD2_Antibody_022322
Typical results from human peripheral blood lymphocytes stained either with TS1/8 PE used at 5 µL/test (filled histogram) or with an isotype control (open histogram).
  • TS18_GMP_PE_CD2_Antibody_022322
    Typical results from human peripheral blood lymphocytes stained either with TS1/8 PE used at 5 µL/test (filled histogram) or with an isotype control (open histogram).
Compare all formats
Cat # Size Price Quantity Check Availability Save
260092 100 tests 229€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD2 is a 50 kD type I transmembrane glycoprotein also known as LFA-2, T11, and sheep red blood cell receptor (SRBC-R). This immunoglobulin superfamily member is expressed on thymocytes, T lymphocytes, NK cells, and thymic B cell subsets. The major ligand for CD2 is CD58 (also known as LFA-3). CD2 has also been reported to bind CD48, CD59, and CD15. CD2 plays a critical role in alternative T cell activation, T cell signaling, and cell-cell adhesion.

Product Details
Technical data sheet

Product Details

Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide, 0.2% (w/v) BSA (origin USA), and a stabilizer
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
25 µg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: blocking of T cell activation, and partial blocking of B cell costimulation2. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 309235 & 309236).

Application References

(PubMed link indicates BioLegend citation)
  1. Schlossman S, et al. Eds.1995. Leucocyte Typing V Oxford University Press. New York.
  2. Hughes CCW, et al. 1996. J. Biol. Chem. 271:5369.
RRID
AB_2910371 (BioLegend Cat. No. 260092)
Disclaimer

GMP RUO Flow Cytometry Antibodies. BioLegend GMP RUO fluorophore conjugated antibodies are manufactured in a dedicated GMP facility and compliant with ISO 13485:2016. For research use only. Not for use in diagnostic or therapeutic procedures.

Our processes include:

  • Batch-to-batch consistency
  • Material traceability
  • Documented procedures
  • Documented employee training
  • Equipment maintenance and monitoring records
  • Lot-specific certificates of analysis
  • Quality audits per ISO 13485:2016
  • QA review of released products

Antigen Details

Structure
Ig superfamily, type I transmembrane glycoprotein, 50 kD
Distribution

T cells, NK cells, thymocytes, and thymic B cell subsets

Function
T cell activation, adhesion
Ligand/Receptor
CD58 (LFA-3), CD48, CD59, CD15
Cell Type
B cells, NK cells, T cells, Thymocytes
Biology Area
Costimulatory Molecules, Immunology
Molecular Family
CD Molecules
Antigen References
  1. Bell G, et al. 1995. J Immunol. 155:2805-7.
  2. Bierer B, et al. 1989. Annu Rev Immunol. 7:579-99.
  3. Moingeon P, et al. 1989. Immunol Rev. 111:111-44.
Gene ID
914 View all products for this Gene ID
UniProt
View information about CD2 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 03.16.2022

For research use only. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses.

 

BioLegend Inc., 8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • FITC anti-human CD2

  • PE anti-human CD2

  • Purified anti-human CD2

  • Pacific Blue™ anti-human CD2

  • PE/Cyanine7 anti-human CD2

  • Brilliant Violet 421™ anti-human CD2

  • Purified anti-human CD2 (Maxpar® Ready)

  • PerCP/Cyanine5.5 anti-human CD2

  • APC anti-human CD2

  • APC/Fire™ 750 anti-human CD2

  • Alexa Fluor® 700 anti-human CD2

  • TotalSeq™-A0367 anti-human CD2

  • TotalSeq™-C0367 anti-human CD2

  • FITC anti-human CD2

  • TotalSeq™-B0367 anti-human CD2

  • Ultra-LEAF™ Purified anti-human CD2

  • APC/Cyanine7 anti-human CD2

  • PE anti-human CD2

  • TotalSeq™-D0367 anti-human CD2

  • PE/Cyanine7 anti-human CD2

  • PerCP/Cyanine5.5 anti-human CD2

  • GMP PE anti-human CD2

  • APC anti-human CD2

  • APC/Fire™ 750 anti-human CD2

  • Pacific Blue™ anti-human CD2

ProductsHere

Login / Register
Remember me
Forgot your password? Reset password?
Create an Account