- S15046E (See other available formats)
- Regulatory Status
- Other Names
- GPR5, CCXCR1, mXCR1, Lymphotactin receptor, SCM1 receptor, XC chemokine receptor 1
- Rat IgG2a, κ
- Ave. Rating
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- Product Citations
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XCR1, also known as GPR5 or CCXCR1, is a 38 kD G-protein coupled, seven transmembrane receptor. It is the only member of the "C" chemokine receptor family and mediates chemotaxis of XCL1 and XCL2 (lymphotactin-1 and -2). XCR1 is expressed on a subset of CD141+ conventional dendritic cells. XCR1 is also involved in the migration and proliferation of some cancer cells.Product Details
- Antibody Type
- Host Species
- Human XCR1-transfected cells.
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA)
- The antibody was purified by affinity chromatography and conjugated with APC/Cyanine7 under optimal conditions.
- Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
Red Laser (633 nm)
- Product Citations
AB_2894579 (BioLegend Cat. No. 372619)
- Only member of the "C" chemokine receptor family, seven transmembrane receptor, coupled to G protein, 38 kD.
Subset of CD141+ conventional dendritic cells.
- Mediates chemotaxis to XCL1.
- XCL1 and XCL2.
- Cell Type
- Dendritic cells
- Biology Area
- Molecular Family
- Cytokine/Chemokine Receptors, GPCR
- Antigen References
1. Carpentier S, et al. 2016. J. Immunol. Methods 432:35.
2. Hartung E, et al. 2015. J. Immunol. 194:1069.
3. Wang T, et al. 2015. Biochem. Biophys. Res. Commun. 464:635.
4. Crozat K, et al. 2011. J. Immunol. 187:4411.
- Gene ID
- 2829 View all products for this Gene ID
- View information about XCR1 on UniProt.org
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