- MIG-2F5.5 (See other available formats)
- Regulatory Status
- Other Names
- MIG-1, MIG
- Armenian Hamster IgG, κ
- Ave. Rating
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- Product Citations
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MIG, also known as mig-1, CXCL9, is a member of the alpha subfamily of inflammatory chemokine. It is inducible in macrophages, hepatocytes, and endothelial cells by IFN-γ, but not by TNF-α or bacterial lipopolysacchrides (LPS). Mig functions as a chemotactic factor for resting memory and activated T cells, both CD4+ and CD8+, and natural killer cells. Furthermore, it was reported that Mig induced both calcium signals and chemotaxis in activated B cells and that B cell activation induced expression of mouse CXCR3. MIG and CXCR3 may be important not only to recruit T cells to peripheral inflammatory sites, but also in some cases to maximize interactions among activated T cells, B cells, and dendritic cells within lymphoid organs to provide optimal humoral responses to pathogens.Product Details
- Antibody Type
- Host Species
- Armenian Hamster
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
ICFC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. The suggested use of this reagent is ≤0.25 µg per 106 cells in 100 µl volume. It is highly recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633nm / 635nm.
Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.
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- Excitation Laser
Red Laser (633 nm)
(PubMed link indicates BioLegend citation)
- Farsaci B, et al. 2014. Cancer Immunol Res. 2:1090. PubMed
- Product Citations
AB_1877135 (BioLegend Cat. No. 515606)
- A member of the alpha subfamily of inflammatory chemokine.
- Inducible in macrophages, hepatocytes, and endothelial cells by IFN-γ.
- Recruit T cells to peripheral inflammatory sites, maximize interactions among activated T cells, B cells, and dendritic cells within lymphoid organs.
- Cell Type
- Biology Area
- Molecular Family
- Antigen References
1. Thapa M et al. 2008. J. Immunol. 180(2):1098
2. Whiting D et al. 2004. J. Immunol. 172 (12):7417
3. Helbig KJ. et al. 2009. J Virol. 83(2):836
- Gene ID
- 4283 View all products for this Gene ID
- View information about CXCL9 on UniProt.org
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