- W15177A (See other available formats)
- Regulatory Status
- Other Names
- IL-17R, IL-17RA, IL-17AR, IL-17 receptor
- Mouse IgG2a, κ
- Ave. Rating
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- Product Citations
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Six interleukin-17 (IL-17)-family (IL-17A-IL-17F) and five IL-17 receptor (IL-17R)-family (IL-17RA-IL-17RE) members have been reported in mammalian cells. IL-17RA (known as IL-17R, IL-17AR, CD217) is a 128-158 kD type I transmembrane glycoprotein. IL-17R binds to IL-17A (also known as IL-17, and CTLA-8, is a hallmarker of Th17 cells) and IL-17F and mediates the proinflammatory signals through interaction with IL-17RC or IL-17RD. IL-17R has broad tissue distribution, including fibroblasts, epithelial cells, endothelial cells, stromal cells, B cells, T cells, NK cells, monocytes and granulocytes.Product Details
- Antibody Type
- Host Species
- P3U1 cells stably transfected with CD217.
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
AB_2632646 (BioLegend Cat. No. 372302)
- 128-158 kD type I single transmembrane glycoprotein, homodimer or heterodimer with IL-17RC, or associate with IL-17RD.
- Broad tissue distribution, including fibroblasts, epithelial cells, endothelial cells, stromal cells, B cells, T cells, NK cells, monocytes and granulocytes
- Binds IL-17 and mediate IL-17 induced inflammatory responses.
- IL-17A, IL-17F.
- Cell Type
- Neutrophils, Eosinophils
- Biology Area
- Molecular Family
- CD Molecules
- Antigen References
1. Moseley TA, et al. 2003. Cytokine Growth Factor Rev. 14:155.
2. Rong Z, et al. 2009. Cell. Res. 19:208.
3. Toy D, et al. 2006. J. Immunol. 177:36.
- Gene ID
- 23765 View all products for this Gene ID
- View information about CD217 on UniProt.org
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