- QA18A04 (See other available formats)
- Regulatory Status
- Other Names
- LPS receptor
- Mouse IgG1, κ
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- Product Citations
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CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens and in the upregulation of adhesion molecules and cytokines expression in monocytes and neutrophils.Product Details
- Antibody Type
- Host Species
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- The antibody was purified by affinity chromatography.
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Clone QA18A04 antibody is able to completely block binding of clone HCD14 on target cells.
AB_2888828 (BioLegend Cat. No. 324902)
- GPI-linked membrane glycoprotein, 53-55 kD
Monocytes, macrophages, granulocytes
- LPS receptor
- Cell Type
- Granulocytes, Macrophages, Monocytes, Neutrophils
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
- Molecular Family
- CD Molecules
- Antigen References
- Stocks SC, et al. 1990. Biochem J. 268:275-80.
- Wright SD, et al. 1990. Science. 249:1431-3.
- Gene ID
- 929 View all products for this Gene ID
- View information about CD14 on UniProt.org
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