Biotin anti-human MCP-1 (CCL2) Antibody

Pricing & Availability
Poly5360 (See other available formats)
Regulatory Status
Other Names
Monocyte chemoattractant protein-1 (MCP1), Monocyte chemoattractant and activating factor (MCAF), JE, Small inducible cytokine A2 (SCYA2), HC-11 (HC11), P6, Smooth muscle cell chemotactic factor (SMC-CF, SMCCF), CCL2, MCP-1, MCP1,CCL-2, MCP-1/CCL2
Goat Ig
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Product Citations
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536004 50 µg 300€
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MCP-1, also known as CCL2, is a member of the CC chemokine family. It is widely expressed in endothelial cells, smooth muscle cells and monocytes in response to several atherogenic stimulants such as CD40 ligand, platelet derived growth factor (PDGF), interleukin-1β (IL-1β) and oxidized low density lipoprotein. In addition, MCP-1 has been implicated in monocytic infiltration of tissues during several inflammatory diseases, and has been implicated in macrophage-mediated tumor growth suppression in mice. MCP-1 has been shown to have direct effects on tumor cells in an autocrine and paracrine fashion in multiple cancers, including breast, lung, cervical, ovarian, and prostatic. In addition, MCP-1 plays a key role in the regulation of MMPs during transmigration.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Recombinant protein
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.

ELISA Detection - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by ELISA assay. For ELISA Detection applications, a concentration range of 0.01 - 0.5 µg/mL is recommended. To obtain a linear standard curve, serial dilutions of MCP-1 recombinant protein ranging from 1000 to 15.6 pg/mL is recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

The biotinylated Poly5360 antibody is useful as the detection antibody in a sandwich ELISA assay, when used in conjunction with the purified Poly5360 antibody (Cat. No. 536002) as the capture antibody and Recombinant Human MCP-1 (CCL2) (ELISA Std.) (Cat. No. 565001).

AB_2734497 (BioLegend Cat. No. 536004)

Antigen Details

CC chemokine, dimer, 13.8 kD (Mammalian)

Monocytes, vascular endothelial cells, smooth muscle, glomerular mesangial cells

Upregulated by IL-1, TNF-α, PDGF, TGF-β
Monocytes, basophils, T cells, NK cells, immature dendritic cells
CCR2, CCR5, CCR10, D6, possibly L-CCR
Cell Type
Endothelial cells, Monocytes
Biology Area
Cell Biology, Neuroinflammation, Neuroscience
Molecular Family
Antigen References

1. Fitzgerald KA, et al. 2001. The Cytokine FactsBook; Academic Press, San Diego.
2. Bischoff SC, et al. 1992. J. Exp. Med. 175:1271.
3. Charo IF, et al. 1994. Proc. Natl. Acad. Sci. USA. 91:2752.
4. Jiang Y, et al. 1992. J. Immunol. 148:2423.

Gene ID
6347 View all products for this Gene ID
View information about MCP-1 on

Related FAQs

How many biotin molecules are per antibody structure?
We don't routinely measure the number of biotins with our antibody products but the number of biotin molecules range from 3-6 molecules per antibody.
Go To Top Version: 1    Revision Date: 06.28.2018

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • Purified anti-human MCP-1 (CCL2)

  • Biotin anti-human MCP-1 (CCL2)


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