APC anti-mouse DLL4 Antibody

Pricing & Availability
HMD4-1 (See other available formats)
Regulatory Status
Other Names
Armenian Hamster IgG
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Product Citations
Mouse Dll4 transfected cells stained with HMD4-1 APC
  • HMD4-1_APC_022309.jpg
    Mouse Dll4 transfected cells stained with HMD4-1 APC
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130813 25 µg 129€
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130814 100 µg 290€
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The Notch receptors and their ligands are highly conserved from invertebrates to mammals. Delta-like 4 (DLL4) is one of four or five Notch ligands identified. The binding to Notch receptor results in the proteolysis of Notch and movement of intracellular portions of Notch into the nucleus. This translocation triggers a series of signaling processes. DLL4 is reported to be essential for the regulation of angiogenesis. In thymus, DLL4 is an essential Notch1 ligand responsible for T cell lineage commitment.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Armenian Hamster
CHO cells expressing murine DLL4
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Wei Y, et al. 2013. PNAS. 110:3910. PubMed (Block)
Product Citations
  1. Montel-Hagen A, et al. 2020. Cell Rep. 33:108320. PubMed
  2. Singhal P, et al. 2016. Proc Natl Acad Sci U S A. 113: 122 - 127. PubMed
AB_2246026 (BioLegend Cat. No. 130813)
AB_2092982 (BioLegend Cat. No. 130814)

Antigen Details

A single-pass transmembrane (TM) protein consisting of a large extracellular N-terminal which includes the DSL domain, followed by a tandem array of EGF-like repeats (ELRs). After the single TM domain is a novel intracellular domain.

DLL4 is primarily expressed in arterial blood vessels and sprouting endothelial cells. DLL4 is also expressed in thymic epithelial cells.

The Notch receptors and their ligands are highly conserved signaling molecules throughout development. They regulate cell fate of various cell's development, including myogenesis, neurogenesis, and lymphocyte development.
Notch Receptors
Cell Type
Endothelial cells, Epithelial cells
Biology Area
Antigen References

1. Ehebauer MT, et al. 2006. Biochem J. 392:13.
2. Shimizu K, et al. 2000. Mol Cell Biol. 20:6913.
3. Hellstrom M, et al. 2007. Nature 445:776.
4. Suchting S, et al. 2007. P. Natl. Acad. Sci. USA 104:3225.

Gene ID
54485 View all products for this Gene ID
View information about Delta-like 4 on UniProt.org

Related FAQs

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Go To Top Version: 1    Revision Date: 11.30.2012

For Research Use Only. Not for diagnostic or therapeutic use.


This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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