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- Clone
- 7B7/FcRL6 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- FcRL6, Fc receptor like 6
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood lymphocytes were stained with anti-human CD56 Brilliant Violet 421™ and anti-human FcRL6 (clone 7B7/FcRL6) APC (left) or mouse IgG1, κ isotype control APC (right).
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 373903 | 25 tests | $190 | ||||
| 373904 | 100 tests | $414 | ||||
FcRL6, a member of Fc receptor-like family, does not bind Ig. It is expressed on cytotoxic NK and a subset of T cells (primarily CD8+ T cells). Its expression level correlates with the differentiation state of these cells. This Type I transmembrane glycoprotein consists of three Ig-like domains on its extracellular and a consensus ITIM or non-canonical ITAM-like sequence on its cytoplasmic region. Patients with chronic lymphocytic leukemia show higher abundance of this receptor due to expansion of cytotoxic lymphocyte population.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- BW5147 transduced with HA-tagged FcRL6
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Red Laser (633 nm)
-
Application References
(PubMed link indicates BioLegend citation) -
- Schreeder DM, et al. 2008. Eur. J. Immunol. 38:3159. (FC)
- RRID
-
AB_2876702 (BioLegend Cat. No. 373903)
AB_2876702 (BioLegend Cat. No. 373904)
Antigen Details
- Structure
- Type I transmembrane glycoprotein, Ig gene superfamily
- Distribution
-
NK, T subset
- Cell Type
- NK cells, T cells
- Biology Area
- Immunology
- Molecular Family
- Fc Receptors
- Antigen References
-
1. Davis RS. 2007. Annu. Rev. Immunol. 25:525.
2. Wilson TJ, et al. 2007. Blood 109:3786.
3. Schreeder DM, et al. 2008. 38:3159. - Gene ID
- 343413 View all products for this Gene ID
- UniProt
- View information about FcRL6 on UniProt.org
Related FAQs
Other Formats
View All FcRL6 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human FcRL6 | 7B7/FcRL6 | FC |
| APC anti-human FcRL6 | 7B7/FcRL6 | FC |
| PE anti-human FcRL6 | 7B7/FcRL6 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human FcRL6
Human peripheral blood lymphocytes were stained with CD56 Al... 
-
APC anti-human FcRL6
Human peripheral blood lymphocytes were stained with anti-hu... -
PE anti-human FcRL6
Human peripheral blood lymphocytes were stained with anti-hu...
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