- 5E5-G5 (See other available formats)
- Regulatory Status
- Other Names
- Histone H3.1, histone H3/a, histone 1, H3/a, H3 histone family, member A
Covance Catalog# MMS-5078
- Mouse IgG1, κ
- Ave. Rating
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- Product Citations
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Histone H3 is a 17 kD nuclear protein that is a component of an octamer containing pairs of each of four core histones (H2A, H2B, H3, H4). The core histones create nucleosome structure of chromosomal fiber in eukaryotes and are dynamic in gene regulation. The histones exhibit cell cycle-dependent transcriptional regulation except for the variant H3.3 which is cell cycle-independent. Histone H3 can be modified by phosphorylation, acetylation, ubiquitination, ribosylation, and methylation. Histone H3 has been shown to interact with Rsk-2, MSK1, GCN5 family of HATs, HDACs, PARP, SET7/9, and CARM1.Product Details
- Human, Rat
- Antibody Type
- Host Species
- This monoclonal antibody was raised against a synthetic peptide from Human Histone H3, di-methylated at Lysine-9.
- Phosphate-buffered solution.
- The antibody was purified by affinity chromatography.
- 1 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
WB - Quality tested
IHC-P - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 - 10 µg per ml. For immunohistochemistry on formalin-fixed paraffin-embedded tissue, a concentration range of 5.0 - 10 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
AB_2564793 (BioLegend Cat. No. 815501)
- Expected MW: 17 kD
- Biology Area
- Cell Biology, Neuroscience, Signal Transduction
- Antigen References
- Murzina N, et al. 2008. Structure. 16:1077.
- Chen S, et al. 2015. Genes & Dev. 29:1326.
- Gene ID
- 8350 View all products for this Gene ID
- View information about Histone H3 Dimethyl Lys9 on UniProt.org
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