- N355/1 (See other available formats)
- Regulatory Status
- Other Names
- GluA1/GluR1 glutamate receptor, Glutamate receptor 1, GluR1, gluR-1, gluR-K1, glutamate receptor A, glutamate receptor subunit GluR1, AMPA-selective glutamate receptor 1, glutamate receptor, ionotropic, AMPA1 (alpha 1)
Covance Catalog# MMS-5143
- Mouse IgG1, κ
- Ave. Rating
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- Product Citations
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GluR1 belongs to the family of Glutamate Receptors (GluRs) that are essential for regulating excitatory synaptic transmission by L-glutamate in the CNS of vertebrates. These are mostly expressed in granule and pyramidal cells in the hippocampus. GluRs can be categorized as ionotropic or metabotropic and subcategorized by their specific agonists (NMDA, AMPA or Kainic acid). There are four types of AMPA related GluR subunits (GluR1, GluR2, GluR3 and GluR4) that are generated by alternative RNA splicing. Tetrameric or pentameric combinations of different subunits contribute to the functional diversity of AMPA receptors.Product Details
- Verified Reactivity
- Mouse, Rat
- Antibody Type
- Host Species
- This monoclonal antibody was raised against a fusion protein corresponding to amino acids 1-389 (extracellular, N-terminus) of rat GluA1/GluR1 glutamate receptor.
- Phosphate-buffered solution.
- The antibody was purified by affinity chromatography.
- 1 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
WB - Quality tested
IHC-P - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 5.0 - 10.0 µg per ml. For immunohistochemistry of formalin-fixed paraffin-embedded tissue, a concentration of 10.0 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
AB_2734581 (BioLegend Cat. No. 819802)
AB_2564834 (BioLegend Cat. No. 819801)
- Expected MW: 100 kD
- Cell Type
- Glutamatergic Neurons
- Biology Area
- Cell Biology, Neuroscience, Neuroscience Cell Markers, Synaptic Biology
- Molecular Family
- Postsynaptic proteins
- Gene ID
- 50592 View all products for this Gene ID
- View information about GluA1/GluR1 glutamate receptor on UniProt.org
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