- QA18A25 (See other available formats)
- Regulatory Status
- Other Names
- IL-3Rα, IL-3 Receptor alpha
- Mouse IgG1, κ
- Ave. Rating
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- Product Citations
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CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.Product Details
- Verified Reactivity
- Antibody Type
- Host Species
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
- Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Clone QA18A25 can completely block the binding of clone 6H6 on target cells.
AB_2924558 (BioLegend Cat. No. 365403)
AB_2924558 (BioLegend Cat. No. 365404)
- Ig superfamily, type I transmembrane glycoprotein, associates with CDw131, 70 kD
Myeloid precursors, basophils, mast cells, macrophages, dendritic cells, megakaryocytes, subset of lymphocytes
- Hematopoietic cell proliferation, differentiation
- Basophils, Dendritic cells, Hematopoietic stem and progenitors, Lymphocytes, Macrophages, Mast cells, Megakaryocytes
- Cell Type
- Antigen-presenting cells, B cells, Basophils, Dendritic cells, Hematopoietic stem and progenitors, Lymphocytes, Macrophages, Mast cells, Megakaryocytes
- Biology Area
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
- Miyajima A, et al. 1993. Blood. 82:1960.
- Gene ID
- 3563 View all products for this Gene ID
- View information about CD123 on UniProt.org
Related Pages & Pathways
Other FormatsView All CD123 Reagents Request Custom Conjugation
|Purified anti-human CD123 Recombinant Antibody||QA18A25||FC|
|PE/Cyanine7 anti-human CD123 Recombinant Antibody||QA18A25||FC|
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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