PE anti-human CD294 (CRTH2) Antibody

Pricing & Availability
BM16 (See other available formats)
Regulatory Status
Other Names
Chemoattractant receptor-homologous molecule expressed on Th2 cells, GPR44, G-protein coupled receptor 44, DP2
Rat IgG2a, κ
Ave. Rating
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Product Citations
Human peripheral blood lymphocytes were stained with CD4 APC, CCR4 PerCP/Cy5.5, and CD294 (clone BM16) PE (top) or rat IgG2a, κ PE isotype control (bottom). Data shown was gated on the CD4+ cell population.
  • BM16_PE_1_113011
    Human peripheral blood lymphocytes were stained with CD4 APC, CCR4 PerCP/Cy5.5, and CD294 (clone BM16) PE (top) or rat IgG2a, κ PE isotype control (bottom). Data shown was gated on the CD4+ cell population.
  • BM16_PE_2_113011
See PE spectral data
Cat # Size Price Quantity Avail. Save
350105 25 tests 80,00€
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350106 100 tests 208,00€
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CD294, also known as CRTH2, is a seven-transmembrane protein coupled with heterotrimeric G proteins. CRTH2 is the prostaglandin D2 receptor and is expressed by Th2 cells, eosinophils, and basophils. CD294 prevents the apoptosis of Th2 cells and mediates the chemotaxis of CRTH2 expressing cells to the sites of allergic inflammation, such as the asthmatic lung.

Product Details
Technical Data Sheet (pdf)

Product Details

Antibody Type
Host Species
Rat cell line TART/B19-12.10 transfected with human CRTH2
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

This product is sold under license agreement with BML, Inc for research use only.

Application References
  1. Nagata K, et al. 1999. J. Immunol. 162:1278. (FC)
  2. De Fanis U, et al. 2007. Blood 109:4343. (FC)
  3. Tsuda H, et al. 2001. Clin. Exp. Immunol. 123:105. (FC)
  4. Hamada K, et al. 2004. Allergology International 53:179. (FC)
Product Citations
  1. Ohue Y, et al. 2014. Clin Cancer Res. 20:5052. PubMed
  2. Marafini I, et al. 2015. PLoS One. 10:126291. PubMed
  3. Kurose K, et al. 2015. Clin Cancer Res. 21: 4327 - 4336. PubMed
  4. Slovick A, et al. 2016. J Allergy Clin Immunol. S0091-6749(16)31186-1. PubMed
  5. Islas-Vazquez L, et al. 2020. Biology (Basel). 9:00. PubMed
  6. Vanoni G, et al. 2021. eLife. 10:00. PubMed
  7. Lintermans L, et al. 2017. Arthritis Res Ther. 10.1186/s13075-017-1343-8. PubMed
  8. Halim TYF et al. 2018. Immunity. 48(6):1195-1207 . PubMed
  9. Galle-Treger L, et al. 2019. Nat Commun. 10:713. PubMed
AB_10900255 (BioLegend Cat. No. 350105)
AB_10900060 (BioLegend Cat. No. 350106)

Antigen Details

Seven-transmembrane protein coupled with G proteins

Effector T helper 2 (Th2) cells, eosinophils, basophils

Chemotaxis of eosinophils, basophils and Th2 cells, prevention of apoptosis in Th2 cells
Heterotrimeric G proteins
Prostaglandin D2
Cell Type
Th2, Eosinophils, Basophils
Biology Area
Cell Biology, Cell Motility/Cytoskeleton/Structure, Immunology
Molecular Family
CD Molecules
Antigen References

1. Luster AD and Tager AM. 2004. Nat. Rev. Immunol. 4:711.
2. Monneret G, et al. 2001. Blood 98:1942.
3. Xue L, et al. 2009. J. Immunol. 182:7580.
4. Schratl P, et al. 2007. J. Immunol. 179:4792.

Gene ID
11251 View all products for this Gene ID
View information about CD294 on

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11-30-2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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