FITC anti-human CD98 Antibody

Pricing & Availability
MEM-108 (See other available formats)
Regulatory Status
Other Names
4F2, FRP-1, RL-388
Mouse IgG1, κ
Ave. Rating
Submit a Review
Product Citations
Human peripheral blood lymphocytes stained with MEM-108 FITC
  • MEM-108_FITC_020708
    Human peripheral blood lymphocytes stained with MEM-108 FITC
Compare all formats See FITC spectral data
Cat # Size Price Quantity Check Availability Save
315603 25 tests 81€
Check Availability

Need larger quantities of this item?
Request Bulk Quote

CD98 is a 125 kD disulfide-linked heterodimer protein also known as 4F2 and FRP-1. It is broadly expressed on activated and transformed cells (hematopoietic and non-hematopoietic), and at low levels on quiescent cells. CD98 has been characterized as a potential amino acid transporter (neutral and dibasic amino acids) that is involved in lymphocyte activation and integrin signaling. CD98 is composed of a light chain (45 kD) and a heavy chain (80 kD). Studies with knock-out mice indicate that the CD98 heavy chain is involved in integrin-dependent cell spreading and protection against anchorage deprivation-induced apoptosis. The MEM-108 antibody is useful for flow cytometry and immunoprecipitation.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Burkitt's lymphoma cell line Raji
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation.

Application References
  1. Kishimoto T, et al. Eds. 1997. Leucocyte Typing VI. Garland Publishing Inc. New York.
  2. Cantor J, et al. 2011. J. Immunol. 187:851. PubMed.
Product Citations
  1. Porat-Shliom N, et al. 2013. PLoS One. 25:81897. PubMed
  2. Nguyen DJM, et al. 2020. Mol Cancer Res. 0.822916667. PubMed
  3. Chakraborty M, et al. 2021. Cell Reports. 34(2):108609. PubMed
AB_2190795 (BioLegend Cat. No. 315603)

Antigen Details

Disulfide-linked heterodimer, 80 kD and 45 kD reduced, 125 kD unreduced

Broadly expressed on activated and transformed cells, not hematopoietic cell-specific. Lower levels on resting cells

Potential amino acid transporter (neutral and dibasic amino acids) also involved in the activation of lymphocytes and integrin signaling. May be a target antigen for NK cells
Actin, β1 integrins (α2β1, α3β1, α5β1, α6β1; minimally with α4β1)
Glycosylated (heavy chain)
Biology Area
Molecular Family
CD Molecules
Antigen References

1. Leukocyte Typing VI. Kishimoto T, et al. (Eds.) Garland Publishing Inc. (1997)
2. Bron C, et al. 1986. J. Immunol. 137:397.
3. Lumadue JA, et al. 1987. Proc. Natl. Acad. Sci. 84:9204.
4. Mastroberardino L, et al. 1998. Nature 395:288.

Gene ID
6520 View all products for this Gene ID
View information about CD98 on

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11-30-2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


8999 BioLegend Way, San Diego, CA 92121
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • Purified anti-human CD98

  • FITC anti-human CD98

  • TotalSeq™-A0374 anti-human CD98

  • TotalSeq™-C0374 anti-human CD98

  • TotalSeq™-B0374 anti-human CD98


Login / Register
Remember me
Forgot your password? Reset password?
Create an Account