FITC anti-human CD86 Antibody

Pricing & Availability
BU63 (See other available formats)
Regulatory Status
HCDM listed
Other Names
B7-2, B70, Ly-58
Mouse IgG1, κ
Ave. Rating
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Product Citations
Human peripheral blood monocytes stained with CD14 APC/Cy7 and human CD86 (clone BU63, top) FITC or Mouse IgG1, κ FITC isotype control (bottom).
  • BU63_FITC_CD86_Antibody_1_102717
    Human peripheral blood monocytes stained with CD14 APC/Cy7 and human CD86 (clone BU63, top) FITC or Mouse IgG1, κ FITC isotype control (bottom).
  • BU63_FITC_CD86_Antibody_2_102717
Compare all formats See FITC spectral data
Cat # Size Price Quantity Check Availability Save
374203 25 tests 85€
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374204 100 tests 212€
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CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
ARH 77 (B lymphoblastoid cell line).
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Product Citations
  1. Liu JJ, et al. 2022. Immun Inflamm Dis. 10:e735. PubMed
  2. Miller CL, et al. 2022. Cell Chem Biol. 29:451. PubMed
  3. Jiang Y, et al. 2023. Sci Adv. 9:eadc8933. PubMed
  4. Toriyama M, et al. 2023. Front Mol Biosci. 10:1149828. PubMed
  5. Yan F, et al. 2022. Cancer Discov. 12:792. PubMed
  6. Vereertbrugghen A, et al. 2021. Front Oncol. 11:598319. PubMed
  7. M?czy?ska J, et al. 2020. Cell Death Dis. 1.073611111. PubMed
  8. Guo Z, et al. 2022. NPJ Precis Oncol. 6:34. PubMed
  9. Rao X, et al. 2022. Cell Death Dis. 13:891. PubMed
  10. Obradovic A, et al. 2021. Cell. 184(11):2988-3005.e16. PubMed
  11. Jost M, et al. 2021. eLife. 10:00. PubMed
  12. Bourdely P, et al. 2020. Immunity. 53(2):335-352. PubMed
  13. Gu C, et al. 2021. Front Immunol. 12:678036. PubMed
  14. Du B, et al. 2020. Scand J Immunol. 91:e12872. PubMed
  15. Wang X, et al. 2022. Cancer Gene Ther. Online ahead of print. PubMed
  16. Luque-Martin R, et al. 2021. J Immunol. 207:555. PubMed
AB_2721573 (BioLegend Cat. No. 374203)
AB_2721574 (BioLegend Cat. No. 374204)

Antigen Details

Ig superfamily, single-chain transmembrane glycoprotein, 80 kD

Monocytes/macrophages, activated B cells and T cells, dendritic cells

T Cell activation
C-Jun, NFκB
CD28, CD152
Cell Type
B cells, Dendritic cells, Macrophages, Monocytes, T cells
Biology Area
Cell Biology, Costimulatory Molecules, Immunology, Neuroscience, Neuroscience Cell Markers
Molecular Family
CD Molecules, Immune Checkpoint Receptors
Antigen References

1. Hathcock K, et al. 1996. Adv. Immunol. 62:131. 
2. June C, et al. 1994. Immunol. Today 15:321.

Gene ID
942 View all products for this Gene ID
View information about CD86 on

Related FAQs

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Go To Top Version: 0    Revision Date: 10-31-2017

For Research Use Only. Not for diagnostic or therapeutic use.


This product is supplied subject to the terms and conditions, including the limited license, located at ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.


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