APC anti-human CD69, CD69, FN50

Pricing & Availability

Analyte Specific Reagent. Analytical and performance characteristics are not established.

Clone: FN50
Workshop: IV A91
Other Names: Very Early Activation Antigen (VEA), Activation inducer molecule (AIM)
Isotype: Mouse IgG1, κ

FN50_APC_CD69_ASR_Antibody_030922 — Typical results from Cell Activation Cocktail (without Brefeldin A, BioLegend Cat. No. 423301) stimulated (3 hours) human peripheral blood lymphocytes stained either with FN50 APC used at 5 µL/test (filled histogram) or with an isotype control (open histogram).

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985206

500 µL

296€

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Description

CD69 is a 27-33 kD type II transmembrane protein also known as activation inducer molecule (AIM), very early activation antigen (VEA), and MLR3. It is a member of the C-type lectin family, expressed as a disulfide-linked homodimer. Other members of this receptor family include NKG2, NKR-P1 CD94, and Ly49. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. CD69 is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells, and certain CD4⁺ T cells in germinal centers of normal lymph nodes. CD69 is involved in early events of lymphocyte, monocyte, and platelet activation, and has a functional role in redirected lysis mediated by activated NK cells.

Product Details

Technical Data Sheet (pdf)

Product Details

Reactivity

Human

Formulation

Phosphate-buffered solution, pH7.2, containing 0.09% sodium azide, 0.2% (w/v) BSA (origin USA), and a stabilizer.

Preparation

The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.

Concentration

100 µg/mL

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

Suggested for Flow Cytometry

Disclaimer

WARNINGS AND PRECAUTIONS

Use appropriate personal protective equipment and safety practices per universal precautions when working with this reagent. Refer to the reagent safety data sheet.
This antibody contains sodium azide. Follow federal, state and local regulations to dispose of this reagent. Sodium azide build-up in metal wastepipes may lead to explosive conditions; if disposing of reagent down wastepipes, flush with water after disposal.
All specimens, samples and any material coming in contact with them should be considered potentially infectious and should be disposed of with proper precautions and in accordance with federal, state and local regulations.
Do not use this reagent beyond the expiration date stated on the label.
Do not use this reagent if it appears cloudy or if there is any change in the appearance of the reagent as these may be an indication of possible deterioration.
Avoid prolonged exposure of the reagent or stained cells to light.

Antigen Details

Antigen References

Schlossman S, et al. 1995. Oxford University Press.
Testi R, et al. 1994. Immunol Today. 15:479-83.

Documentation

Certificate of Analysis

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Go To Top Version: 1 Revision Date: 03-14-2022

Analyte Specific Reagent. Analytical and performance characteristic are not established.

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