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Alexa Fluor® 647 anti-human CD79b (Igβ) Antibody

Pricing & Availability
Clone
CB3-1 (See other available formats)
Regulatory Status
RUO
Workshop
VI CD79.1
Other Names
Igb, Igβ (Ig-beta), B29
Isotype
Mouse IgG1, κ
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Product Citations
publications
CB3-1_A647_CD79b_Antibody_1_122216
Human peripheral blood lymphocytes were stained with CD19 PE and CD79b (clone CB3-1) Alexa Fluor® 647 (top) and mouse IgG1, κ Alexa Fluor® 647 isotype control (bottom).
  • CB3-1_A647_CD79b_Antibody_1_122216
    Human peripheral blood lymphocytes were stained with CD19 PE and CD79b (clone CB3-1) Alexa Fluor® 647 (top) and mouse IgG1, κ Alexa Fluor® 647 isotype control (bottom).
  • CB3-1_A647_CD79b_Antibody_2_122216
Compare all formats See Alexa Fluor® 647 spectral data
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341409 25 tests 118€
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341410 100 tests 278€
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Description

CD79 is a heterodimeric molecule comprised of an α-chain (CD79a) and β-chain (CD79b). A 37-39 kD type I integral membrane protein CD79b is non-covalently associated with CD79a and cell surface IgM to form the B-cell receptor (BCR) complex. CD79b is expressed on the surface of surface Ig (sIg)-positive B cells and in the cytoplasm of sIg-negative B cells. It is essential for signal transduction after surface Ig crosslinking.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

* Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.


Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.

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Excitation Laser
Red Laser (633 nm)
Application References
  1. Nakamura T, et al. 1992. P. Natl. Acad. Sci. USA 89:8522.
  2. Garcia Vela J, et al. 1999. Leukemia. 13:1501.
  3. Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
  4. Rossi EA, et al. 2014. PLoS One. 9:98315. PubMed
RRID
AB_2632946 (BioLegend Cat. No. 341409)
AB_2632947 (BioLegend Cat. No. 341410)

Antigen Details

Structure
37-39 kD type I integral membrane protein, associate with CD79a and cell surface IgM to form the B-cell receptor (BCR) complex, Ig superfamily.
Distribution

B cells

Function
From BCR complex, signal transduction
Cell Type
B cells
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References

1. Zola H, et al. Eds. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. A John Wiley & Sons Inc.
2. Dylke J, et al. 2007. Immunol. Lett. 112:47

Gene ID
974 View all products for this Gene ID
UniProt
View information about CD79b on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 12-22-2016

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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