- 1B4/CD18 (See other available formats)
- Regulatory Status
- Other Names
- Integrin beta-2, integrin beta chain, beta 2
- Mouse IgG2a, κ
- Ave. Rating
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- Product Citations
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CD18 is a 90-95 kD type I transmembrane protein also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in adhesion and signaling in hematopoietic cells.Product Details
- Verified Reactivity
- Antibody Type
- Host Species
- Human peripheral blood lymphocytes
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
* Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.
Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.
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- Excitation Laser
Blue Laser (488 nm)
- Application Notes
The 1B4/CD18 antibody was able to partially block the Ts1/18 antibody, indicating the two anti-CD18 antibodies recognize distinct but overlapping epitopes.
- Application References
- Singer II, et al. 1993. J. Immunol. 150:2844.
- Seth R, et al. 1991. FEBS Lett. 282:193.
AB_2716019 (BioLegend Cat. No. 373403)
AB_2716020 (BioLegend Cat. No. 373404)
- Integrin, type I transmembrane glycoprotein
- Adhesion and signaling in hematopoietic cells
- Associates with CD11a, CD11b, or CD11c
- Cell Type
- Leukocytes, Tregs
- Biology Area
- Cell Adhesion, Cell Biology, Immunology, Signal Transduction
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
1. Hogg N, et al. 1999. J. Clin. Invest. 103:97.
2. Anderson DC, et al. 1987. Annu. Rev. Med. 38:175.
3. Springer TA. 1994. Cell 76:301.
- Gene ID
- 3689 View all products for this Gene ID
- View information about CD18 on UniProt.org
|Purified anti-human CD18||1B4/CD18||FC|
|APC anti-human CD18||1B4/CD18||FC|
|PE/Cyanine7 anti-human CD18||1B4/CD18||FC|
|Alexa Fluor® 488 anti-human CD18||1B4/CD18||FC|
|PE anti-human CD18||1B4/CD18||FC|
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