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- Clone
- N18/28 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Disks large homolog 2, chapsyn-110, discs large homolog 2, synaptic density protein PSD-93, postsynaptic density protein PSD-93, channel-associated protein of synapse-110, PSD93
- Previously
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Covance Catalog# MMS-5129
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
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Western blot of purified anti-PSD-93 (Chapsyn-110) antibody (clone N18/28). Lane 1: Molecular weight marker; Lane 2: 20 µg of human brain membrane lysate; Lane 3: 20 µg of mouse brain membrane lysate; Lane 4: 20ug of rat brain membrane lysate. The blot was incubated with 1 µg/mL of the primary antibodies overnight at 4°C, followed by incubation with HRP labeled goat anti-mouse IgG (Cat. No. 405306). Enhanced chemiluminescence was used as the detection system. -
IHC staining of purified anti-PSD-93 (Chapsyn-110) antibody (clone N18/28) on formalin-fixed paraffin-embedded mouse brain tissue. Following antigen retrieval using Sodium Citrate H.I.E.R., the tissue was incubated with 10 µg/ml of the primary antibody overnight at 4°C. BioLegend's Ultra-Streptavidin HRP kit (Cat. No. 929901) was used for detection followed by hematoxylin counterstaining, according to the protocol provided. The image was captured with a 40X objective. Scale bar: 50 µm -
IHC staining of anti-PSD-93 (Chapsyn-110) antibody (clone N18/28) on formalin-fixed paraffin-embedded rat brain tissue. Following antigen retrieval using Sodium Citrate H.I.E.R., the tissue was incubated with 10 µg/ml of the primary antibody overnight at 4°C. BioLegend's Ultra-Streptavidin HRP kit (Cat. No. 929901) was used for detection followed by hematoxylin counterstaining, according to the protocol provided. The image was captured with a 40X objective. Scale bar: 50 µm
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 818302 | 25 µL | 67€ | ||||
| 818301 | 100 µL | 132€ | ||||
PSD-93, also known as DLG2 or Chapsyn-110, is a member of the MAGUK family important in the scaffolding of receptors with adhesion molecules on the postsynaptic membrane. It regulates surface expression of receptors by directly interacting with the cytoplasmic tail of NMDA receptor subunits and inward rectifying potassium channels, and is involved in the regulation of synaptic stability at synapses.
Product DetailsProduct Details
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This monoclonal antibody was raised against a full-length fusion protein (amino acids 1-852) of rat Chapsyn-110 protein.
- Formulation
- Phosphate-buffered solution.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 1 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
- Application
-
WB - Quality tested
IHC-P - Verified - Recommended Usage
-
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 µg per ml. For immunohistochemistry, a concentration of 10 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
This antibody is less reactive in human.
The antibody does not cross-react wtih SAP97, SAP102, or PSD-95. - Product Citations
-
- RRID
-
AB_2734574 (BioLegend Cat. No. 818302)
AB_2564819 (BioLegend Cat. No. 818301)
Antigen Details
- Structure
- Expected MW: 110 kD
- Cell Type
- Neurons
- Biology Area
- Cell Biology, Neuroscience, Synaptic Biology
- Molecular Family
- Cytoskeletal Proteins, Postsynaptic proteins, Scaffold Proteins
- Gene ID
- 64053 View all products for this Gene ID
- UniProt
- View information about PSD-93 on UniProt.org
Related FAQs
Other Formats
View All PSD-93 (Chapsyn-110) Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-PSD-93 (Chapsyn-110) | N18/28 | WB,IHC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-PSD-93 (Chapsyn-110)
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