- B-D48 (See other available formats)
- Regulatory Status
- Other Names
- PRF1, P1, PFP, HPLH2
- Mouse IgG1
- Ave. Rating
- Submit a Review
- Product Citations
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Perforin is a 70 kD cytolytic protein that is expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. Perforin is one of the major effector molecules used by cytotoxic T cells and NK cells to mediate targeted cell lysis.Product Details
- Verified Reactivity
- Antibody Type
- Host Species
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
ICFC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.
Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.
View full statement regarding label licenses
- Excitation Laser
Red Laser (633 nm)
- Product Citations
AB_2783256 (BioLegend Cat. No. 353321)
AB_2783257 (BioLegend Cat. No. 353322)
- 70 kD
CTL, NK (cytoplasmic granules)
- Mediates targeted cell lysis.
- Cell Type
- NK cells, Tregs
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neuroscience
- Molecular Family
- Antigen References
1. Lieberman J. 2003. Nat. Rev. Immunol. 3:361.
2. Trapani J, et al. 2002. Nat. Rev. Immunol. 2:735.
- Gene ID
- 5551 View all products for this Gene ID
- View information about Perforin on UniProt.org
Related Pages & Pathways
Other FormatsView All Perforin Reagents Request Custom Conjugation
|Brilliant Violet 421™ anti-human Perforin||B-D48||ICFC|
|PE anti-human Perforin||B-D48||ICFC|
|Pacific Blue™ anti-human Perforin||B-D48||ICFC|
|APC anti-human Perforin||B-D48||ICFC|
|PerCP/Cyanine5.5 anti-human Perforin||B-D48||ICFC|
|PE/Cyanine7 anti-human Perforin||B-D48||ICFC|
|FITC anti-human Perforin||B-D48||ICFC|
|Alexa Fluor® 700 anti-human Perforin||B-D48||ICFC|
|APC/Fire™ 750 anti-human Perforin||B-D48||ICFC|
|Alexa Fluor® 488 anti-human Perforin||B-D48||ICFC|
|Alexa Fluor® 647 anti-human Perforin||B-D48||ICFC|
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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Brilliant Violet 421™ anti-human Perforin
PE anti-human Perforin
Pacific Blue™ anti-human Perforin
APC anti-human Perforin
PerCP/Cyanine5.5 anti-human Perforin
PE/Cyanine7 anti-human Perforin
FITC anti-human Perforin
Alexa Fluor® 700 anti-human Perforin
APC/Fire™ 750 anti-human Perforin
Alexa Fluor® 488 anti-human Perforin
Alexa Fluor® 647 anti-human Perforin