Products

 

Our Flex-T™ reagents include biotinylated monomers containing UV-labile peptides or pre-loaded with fixed peptides, ELISA reagents to evaluate the efficiency of peptide exchange, and custom monomers and tetramers. Click each product family below to view the full list of available products.

 

Mouse Class I Biotinylated Monomers- Fixed Peptides

 

Human Class I Biotinylated Monomers- UV-labile Peptides

 

Human Class I Biotinylated Monomers- Fixed Peptides

 

ELISA Reagents

 

Custom Monomers and Tetramers

 

 

To order custom products please fill out the Custom Flex-T™ Request Form

 

Reagents are for research use only. Any use of the reagents for commercial applications require an additional license agreement. Please contact BioLegend Business Development for more information.

 

Mouse Class I Biotinylated Monomer- Fixed Peptide Size Antigen Epitope Position
Flex-T™ Biotin H-2 K(b) OVA Monomer (SIINFEKL) 25 μg Ovalbumin 323-339
Flex-T™ Biotin H-2 K(d) EGFP Monomer (HYLSTQSAL) 25 μg Enhanced green fluorescent protein 200-208
Flex-T™ Biotin H-2 D(b) LCMV Monomer (FQPQNGQFI) 25 μg LCMV, Nucleoprotein 396-404
Flex-T™ Biotin H-2 D(b) LCMV Monomer (KAVYNFATC) 25 μg LCMV, Pre-glycoprotein polyprotein GP complex 33-41
Flex-T™ Biotin H-2 K(b) LCMV Monomer (ISHNFCNL) 25 μg LCMV, Pre-glycoprotein polyprotein GP complex 118-125
Flex-T™ Biotin H-2 D(b) PMV Monomer (GAPRNRELF) 25 μg Murine orthopneumovirus, Nucleocapsid 339-347
Flex-T™ Biotin H-2 K(b) Sendai Monomer (FAPGNYPAL) 25 μg Murine respirovirus, nucleoprotein 324–332
Flex-T™ Biotin H-2 K(b) VV Monomer (TSYKFESV) 25 μg Vaccinia virus, Soluble interferon gamma receptor B8 20-27
Flex-T™ Biotin H-2 D(b) Flu Monomer (SSLENFRAYV) 25 μg Influenza A virus, Polymerase acidic protein 224-233
Flex-T™ Biotin H-2 D(b) Flu Monomer (ASNENMETM) 25 μg Influenza A virus, Nucleoprotein 366-374
Flex-T™ Biotin H-2 K(b) TRP2 Monomer (SVYDFFVWL) 25 μg Human L-dopachrome tautomerase 180-188
Flex-T™ Biotin H-2 K(d) HIV Monomer (AMQMLKETI) 25 μg HIV, Gag-Pol polyprotein 199-207

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Human Class I Biotinylated Monomer- UV-labile Peptide Size
Flex-T™ HLA-A*01:01 Monomer UVX 50 µg
Flex-T™ HLA-A*02:01 Monomer UVX 50 µg | 200 µg
Flex-T™ HLA-A*02:03 Monomer UVX 50 µg
Flex-T™ HLA-A*03:01 Monomer UVX 50 µg
Flex-T™ HLA-A*11:01 Monomer UVX 50 µg
Flex-T™ HLA-A*24:02 Monomer UVX 50 µg
Flex-T™ HLA-B*07:02 Monomer UVX 50 µg
Flex-T™ HLA-B*08:01 Monomer UVX 50 µg
Flex-T™ HLA-C*04:01 Monomer UVX 50 µg

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Human Class I Biotinylated Monomer- Fixed Peptides Size Antigen Epitope Position
Flex-T™ Biotin HLA-A*02:01 SARS-CoV-2 Monomer (SIIAYTMSL) 25 µg SARS-CoV-2 Spike protein 691-699
Flex-T™ Biotin HLA-A*02:01 SARS-CoV-2 Monomer (GMSRIGMEV) 25 µg SARS-CoV-2 Spike protein 1220-1228
Flex-T™ Biotin HLA-A*02:01 SARS-CoV-2 Monomer (LLLDRLNQL) 25 µg SARS-CoV-2 Spike protein 958-966
Flex-T™ Biotin HLA-A*02:01 SARS-CoV-2 Monomer (FIAGLIAIV) 25 µg SARS-CoV-2 Spike protein 976-984
Flex-T™ Biotin HLA-A*02:01 SARS-CoV-2 Monomer (ALNTLVKQL) 25 µg SARS-CoV-2 Spike protein 1042-1050
Flex-T™ Biotin HLA-A*02:01 SARS-CoV-2 Monomer (VLNDILSRL) 25 µg SARS-CoV-2 Spike protein 996-1004
Flex-T™ Biotin HLA-A*02:01 SARS-CoV-2 Monomer (VVFLHVTYV) 25 µg SARS-CoV-2 Spike protein 1192-1200
Flex-T™ Biotin HLA-A*02:01 SARS-CoV-2 Monomer (TLACFVLAAV) 25 µg SARS-CoV-2 Spike protein 1185-1193
Flex-T™ Biotin HLA-A*02:01 SARS-CoV-2 Monomer (LITGRLQSL) 25 µg SARS-CoV-2 nucleoprotein 316-324
Flex-T™ Biotin HLA-A*02:01 SARS-CoV-2 Monomer (NLNESLIDL) 25 µg SARS-CoV-2 nucleoprotein 222-230
Flex-T™ Biotin HLA-A*02:01 SARS-CoV-2 Monomer (RLNEVAKNL) 25 µg SARS-CoV-2 membrane protein 61-70

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ELISA Reagents Size
LEGEND MAX™ Flex-T™ Human Class I Peptide Exchange ELISA Kit 1 pre-coated plate
Purified Streptavidin 250 µg
HRP anti-human β2-macroglobulin antibody 50 µg
Flex-T™ ELISA Positive Control 20 µg

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Custom Flex-T™ Reagents Size

Flex-T™ Custom HLA Monomer

50 µg | 200 µg

Flex-T™ Custom HLA Tetramer

50 tests | 200 tests

Flex-T™ Custom Mouse Monomers

50 µg | 200 µg

Flex-T™ Custom Mouse Tetramers

50 tests | 200 tests

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Useful links

A collaboration between the Departments of Bio and Health Informatics, the Department of Immunology and Microbiology, from the Copenhagen Business School and the University of Copenhagen, and La Jolla Institute for Allergy and Immunology, has resulted in a software to predict peptide-MHC class I binding using artificial neural networks (ANNs). You can test a peptide sequence here: http://www.cbs.dtu.dk/services/NetMHCpan-4.0/

Reference: https://www.ncbi.nlm.nih.gov/pubmed/28978689

 

The Immune Epitope Database (IEDB) is a free resource from the NIAID that predicts and analyzes epitopes. The database collects experimental data, including published datasets, regarding T cell and antibody epitopes relevant to infectious disease, allergy, autoimmunity, and transplantations. Use the tools at: https://www.iedb.org/home_v3.php