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Purified anti-S100A6 Antibody

Pricing & Availability
Clone
BL28542 (See other available formats)
Regulatory Status
RUO
Other Names
S100A6, Calcyclin, MLN4
Isotype
Mouse IgG2b, κ
Ave. Rating
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Product Citations
publications
BL28542_Purified_S100A6_Antibody_1_111918
Western blot of purified anti-S100A6 antibody (clone BL28542). Lane 1: Molecular weight marker; Lane 2: 10 µg of HeLa cell lysate; Lane 3: 20 µg of HeLa cell lysate; The blot was incubated with 0.5 µg/mL of the primary antibody overnight at 4°C, followed by incubation with HRP-labeled goat anti-mouse IgG (Cat. No. 405306). Enhanced chemiluminescence was used as the detection system.
  • BL28542_Purified_S100A6_Antibody_1_111918
    Western blot of purified anti-S100A6 antibody (clone BL28542). Lane 1: Molecular weight marker; Lane 2: 10 µg of HeLa cell lysate; Lane 3: 20 µg of HeLa cell lysate; The blot was incubated with 0.5 µg/mL of the primary antibody overnight at 4°C, followed by incubation with HRP-labeled goat anti-mouse IgG (Cat. No. 405306). Enhanced chemiluminescence was used as the detection system.
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854201 25 µg 85€
 
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Description

S100 calcium-binding protein A6 (S100A6) is a member of the S100 protein family, ubiquitously expressed in all cell types. S100A6 contains 2 EF-hand motives that bind to Calcium and enable the protein to function as a cellular Ca2+ sensor and regulator. By modulating Ca2+ signaling, S100A6 plays an important role in many physiological processes, including cell migration, process extension and cytoskeleton reorganization.  S100A6 may also be involved in Ca2+-dependent insulin release and prolactin secretion.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
0.01 M PBS, pH 7.4, containing 0.02% NaN3, 50% glycerol.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Application

WB - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2783437 (BioLegend Cat. No. 854201)

Antigen Details

Structure
S100A6 is a 90 amino acid protein with a molecular mass of ~ 10 kD.
Distribution

Tissue Distribution: Ubiquitously expressed.
Cellular distribution: Plasma membrane, cytosol, extracellular, and nucleus.

Function
S100A6 plays an important role in modulating cellular Ca2+ signaling.
Interaction
S100A6 forms homodimer and interacts with CACYBP, ANXA2, ANXA11, SUGT1, TP53, FKBP4, and PPP5C.
Biology Area
Cell Biology, Neuroscience, Synaptic Biology
Molecular Family
Adhesion Molecules
Antigen References
  1. Donato R, et al. 2017. Cell Mol Life Sci. 74(15):2749
  2. Lesniak W, et al. 2017. Biol Chem. 398(10): 1087
  3. Filipek A. 2006. Chemotherapy. 52(1):32
Gene ID
6277 View all products for this Gene ID
UniProt
View information about S100A6 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11/20/2018

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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