- BSB-62 (See other available formats)
- Regulatory Status
- Other Names
- Transcription factor SOX-10
- Mouse IgG2b, κ
- Ave. Rating
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- Product Citations
SOX-10 is a transcriptional activator that is involved in the regulation of embryonic development and in the determination of cell fate.Product Details
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Host Species
- Synthetic peptide corresponding to the N-terminus of human SOX-10.
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
IHC-P - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5.0 - 10 μg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This antibody may show weaker reactivity to human tissues.
- Product Citations
AB_2734617 (BioLegend Cat. No. 847201)
AB_2629666 (BioLegend Cat. No. 847202)
- SOX-10 is a 466 amino acid protein with a molecular mass of 50 kD.
Tissue distribution: primarily expressed in the nuclei of glia in fetal and adult brain, and in the heart, salivary gland and skin.
Cellular distribution: nucleus.
- SOX-10 likely functions synergistically with the POU domain protein TST-1/OCT6/SCIP to confer function of other transcription factors in developing and mature glia. The protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development.
- DNA, PAX3, NMI.
- Cell Type
- Biology Area
- Cell Biology, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- Endosomal Markers
- Antigen References
- Gene ID
- 6663 View all products for this Gene ID
- View information about SOX-10 on UniProt.org
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