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Purified anti-mouse TCR γ/δ Recombinant Antibody

Pricing & Availability
Clone
QA20A46 (See other available formats)
Regulatory Status
RUO
Other Names
TCR-γ/δ, γ/δ TCR
Isotype
Armenian Hamster IgG
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Product Citations
publications
QA20A46_PURE_TCRGammaDelta_Antibody_040522
C57BL/6 mouse splenocytes were stained with purified anti-mouse TCR γ/δ recombinant (clone QA20A46) (left) or purified Armenian hamster IgG isotype control (right) followed by Biotin goat anti-hamster (Armenian) IgG and PE Streptavidin. Cells were costained with anti-mouse CD3 APC.
  • QA20A46_PURE_TCRGammaDelta_Antibody_040522
    C57BL/6 mouse splenocytes were stained with purified anti-mouse TCR γ/δ recombinant (clone QA20A46) (left) or purified Armenian hamster IgG isotype control (right) followed by Biotin goat anti-hamster (Armenian) IgG and PE Streptavidin. Cells were costained with anti-mouse CD3 APC.
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Cat # Size Price Save
111202 100 µg ¥23,320
Description

Gamma-delta (γ/δ) T Cells express γ/δ TCR complex. TCR γ/δ associates with CD3 to recognize certain bacterial and tumor antigens. Most TCR γ/δ are CD4-/CD8- while some are CD8+ and are found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. γ/δ T cells have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Recombinant
Host Species
Armenian Hamster
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide, 50 mM citrate and stabilizer
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone QA20A46 can completely block the binding of clone UC7-13D5 on target cells.

RRID
AB_2924450 (BioLegend Cat. No. 111202)

Antigen Details

Structure
Ig superfamily
Distribution

Subset of T cells

Function
Antigen recognition
Interaction
Associated with CD3 complex
Ligand/Receptor
MHC class I, MHC class I like molecules
Cell Type
Lymphocytes, T cells
Biology Area
Immunology
Molecular Family
TCRs
Antigen References
  1. Skarstein K, et al. 1994. Immunology. 81:497-501.
  2. Harrison LC, et al. 1996. J Exp Med. 184:2167-74.
  3. Wildner G, et al. 1996. Eur J Immunol. 26:2140-8.
  4. Brandes M, et al. 2005. Science. 309:264-8.
  5. Vantourout P, et al. 2013. Nat Rev Immunol. 13:88-100.
Gene ID
110066 View all products for this Gene ID
UniProt
View information about TCR gamma/delta on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 04/05/2022

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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