- IRF4.3E4 (See other available formats)
- Regulatory Status
- Other Names
- Interferon regulatory factor 4
- Rat IgG1, κ
- Ave. Rating
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- Product Citations
The IRF family consists of at least nine members. IRF4 and IRF8 are highly homologous to each other and also redundant in function. IRF4 is critical for Th2 and Th17 development. Together with TRF8, it plays an essential role in macrophage and dendritic cell development and function. IRF4 is also reported to be essential for pre-B cell development, receptor editing, germinal center reactor and plasma cell differentiation.Product Details
- Verified Reactivity
- Mouse, Human
- Antibody Type
- Host Species
- GST fusion protein containing C-terminal of murine IRF4
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
WB - Quality tested
ChIP - Verified
ICFC - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 10 µg/ml. For ChIP applications, the suggested dilution is is 1:50-1:200 by volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats) include: spatial biology (IBEX)3,4.
(PubMed link indicates BioLegend citation)
- Product Citations
AB_2280462 (BioLegend Cat. No. 646402)
- Molecular weight is approximately 51 kD.
IRF4 is reported to be expressed exclusively in the immune system.
- Biology Area
- Cell Biology, Transcription Factors
- Molecular Family
- Nuclear Markers
- Antigen References
1. Lu R. 2008. Trends Immunol 29:487.
- Gene ID
- 3662 View all products for this Gene ID
- View information about IRF4 on UniProt.org
|Alexa Fluor® 488 anti-IRF4||IRF4.3E4||ICFC|
|Purified anti-IRF4||IRF4.3E4||WB, ICFC, ChIP|
|PE anti-IRF4||IRF4.3E4||ICFC, SB|
|Alexa Fluor® 647 anti-IRF4||IRF4.3E4||ICFC|
|Go-ChIP-Grade™ Purified anti-IRF4||IRF4.3E4||ChIP, WB, FC|
|Alexa Fluor® 594 anti-IRF4||IRF4.3E4||ICC|
|Pacific Blue™ anti-IRF4||IRF4.3E4||ICFC|
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