Purified anti-human CD321 (F11R) Antibody

Pricing & Availability
Clone
OV-5B8 (See other available formats)
Regulatory Status
RUO
Other Names
Junctional Adhesion Molecule A, JAM-A, JAM-1, JCAM, F11 R
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
OV-5B8_FITC_110811
HT29 (Human Colon Cancer cell line) cells were stained with CD321 (clone OV-5B8) FITC (filled histogram) or mouse IgG1, κ FITC isotype control (open histogram).
  • OV-5B8_FITC_110811
    HT29 (Human Colon Cancer cell line) cells were stained with CD321 (clone OV-5B8) FITC (filled histogram) or mouse IgG1, κ FITC isotype control (open histogram).
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Cat # Size Price Save
353502 100 µg ¥27,280
Description

CD321, also known as Junctional Adhesion Molecule A (JAM-A), JAM-1, or F11 Receptor, is a 32-40 kD type I transmembrane glycoprotein which belongs to the immunoglobin suerfamily.  It is expressed broadly on leukocytes, platelets, erythrocytes, and epithelial and endothelial cells.  CD321 plays a role in cell adhesion, leukocyte migration, and angiogenesis, through its interactions with integrins, such as LFA-1 and αvβ3 integrins.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
SKOV3 Adenocarcinoma Cell Line
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_10917388 (BioLegend Cat. No. 353502)

Antigen Details

Structure
32-40 kD type I trans-membrane glycoprotein, member of the immunoglobin superfamily
Distribution

Leukocytes, platelets, erythrocytes, epithelial cells, and endothelial cells

Function
Cell adhesion, angiogenesis
Ligand/Receptor
Integrins
Cell Type
Endothelial cells, Epithelial cells, Leukocytes, Platelets
Biology Area
Angiogenesis, Cell Adhesion, Cell Biology, Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Woodfin A, et al. 2007. Blood 110:1848.
2. Cera MR, et al. 2009. J. Cell Sci. 122:268.
3. Fraemohs L, et al. 2004. J. Immunol. 173:6259.
4. Wojcikiewicz EP, et al. 2009. Biophys. J. 96:285.

Gene ID
50848 View all products for this Gene ID
UniProt
View information about CD321 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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