Purified anti-CD105 (Endoglin) Antibody (Previously Covance catalog# SIG-3770)

Pricing & Availability
Clone
SN6h (See other available formats)
Regulatory Status
RUO
Other Names
Endoglin
Previously
Covance Catalog# SIG-3770
Isotype
Mouse IgG1, κ
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Product Citations
publications
SN6h_Pure_CD105-endoglin_Antibody_051718
IHC staining of purified anti-CD105 (Endoglin) antibody (clone SN6h) on formalin-fixed paraffin-embedded human kidney tissue. Following antigen retrieval using Protease 8, the tissue was incubated with primary antibody at 1:40 dilution for 60 minutes at room temperature. BioLegend´s ACUITYAdvanced Biotin Free Polymer Kit (DAB, Cat. No. 931001) was used for detection followed by hematoxylin counterstaining, according to the protocol provided. The image was captured with a 40X objective. Scale bar: 50 µm
  • SN6h_Pure_CD105-endoglin_Antibody_051718
    IHC staining of purified anti-CD105 (Endoglin) antibody (clone SN6h) on formalin-fixed paraffin-embedded human kidney tissue. Following antigen retrieval using Protease 8, the tissue was incubated with primary antibody at 1:40 dilution for 60 minutes at room temperature. BioLegend´s ACUITYAdvanced Biotin Free Polymer Kit (DAB, Cat. No. 931001) was used for detection followed by hematoxylin counterstaining, according to the protocol provided. The image was captured with a 40X objective. Scale bar: 50 µm
Cat # Size Price Save
800501 1 mL ¥93,000
Description

Endoglin (CD105) is a type I membrane glycoprotein that is part of the TGF beta receptor complex. It is expressed in vascular endothelial tissue as well as a variety of other tissues. Endoglin may also be involved in the cytoskeletal organization affecting cell morphology and migration.

Product Details
Technical data sheet

Product Details

Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
EDG (CD105) isolated from acute lymphoblastic leukemia cells.
Formulation
Phosphate-buffered solution with BSA + 0.1% NaN3.
Preparation
The antibody was purified by affinity chromatography.
Storage & Handling
Store between 2°C and 8°C.
Application

IHC-P - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a dilution of 1:40 (concentrated format) is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Concentration Format:
Cat No. 800501 (1 mL)

Application References

(PubMed link indicates BioLegend citation)
  1. Li C, et al. 2003. Br J Cancer. 88:1424.
  2. Sanz-Rodriguez F, et al. 2004. J Biol Chem. 279(31):32858-68.
  3. Takahashi N, et al. 2001. Clin Cancer Res. 7(3):524.
  4. Seon BK, et al. 1997. Clin Cancer Res. 3(7):1031-1044.
  5. Haruta Y & Seon BK. 1986. Proc Natl Acad Sci U S A. 83: 7898.
RRID
AB_2564628 (BioLegend Cat. No. 800501)

Antigen Details

Cell Type
Mesenchymal Stem Cells
Biology Area
Cell Biology, Neuroinflammation, Neuroscience, Stem Cells
Molecular Family
CD Molecules
Gene ID
2022 View all products for this Gene ID
UniProt
View information about CD105 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 3    Revision Date: 05/17/2018

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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