PE anti-mouse CD115 (CSF-1R) Antibody

Pricing & Availability
W19330E (See other available formats)
Regulatory Status
Other Names
CSF-1R, M-CSR, c-fms
Rat IgG2a, κ
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Product Citations
Thioglycolate-elicited BALB/c mouse peritoneal macrophages were stained with PE anti-mouse CD115 (clone W19330E) (filled histogram) or rat IgG2a, κ PE isotype control (open histogram).
  • W19330E_PE_CD115_Antibody_022422
    Thioglycolate-elicited BALB/c mouse peritoneal macrophages were stained with PE anti-mouse CD115 (clone W19330E) (filled histogram) or rat IgG2a, κ PE isotype control (open histogram).
See PE spectral data
Cat # Size Price Save
165203 25 µg ¥19,740

CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Antibody Type
Host Species
Mouse CD115 transfected cells
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
0.2 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Clone W19330E does not affect binding of clone W19330C on target cells.

Clone W19330E can block clone AFS98 binding on target cells.   

Clone W19330E can block ligand binding to CSFR-1.

AB_2910352 (BioLegend Cat. No. 165203)

Antigen Details

Ig superfamily, 145 kD

Monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, osteoclasts 

Growth factor receptor, tyrosine kinase
Macrophage colony stimulating factor (M-CSF), IL-34
Cell Type
Dendritic cells, Macrophages, Monocytes, Osteoclasts
Biology Area
Cell Biology, Immunology, Stem Cells
Molecular Family
Cytokine/Chemokine Receptors
Antigen References
  1. Guilbert LJ and Stanley ER. 1980. J Cell Bio. 85:153-9.
  2. Yeung Y-G, et al. 1978. Proc Natl Acad Sci. 84:1268-71.
  3. Sherr CJ, et al. 1985. Cell. 41:665-76.
Gene ID
12978 View all products for this Gene ID
View information about CD115 on

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 02/24/2022

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • Purified anti-mouse CD115 (CSF-1R)

  • PE anti-mouse CD115 (CSF-1R)


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