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PE anti-mouse CD103 Antibody

Pricing & Availability
Clone
W19396D (See other available formats)
Regulatory Status
RUO
Other Names
CD103, ITAGE, integrin alpha E,
Isotype
Rat IgG2b, κ
Ave. Rating
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Product Citations
publications
W19396D_PE_CD103_Antibody_111722
C57BL/6 mouse splenocytes were stained with anti-mouse CD103 (clone W19396D) PE (left) or rat IgG2b, κ PE isotype control (right). Cells were costained with anti-mouse CD3 APC.
  • W19396D_PE_CD103_Antibody_111722
    C57BL/6 mouse splenocytes were stained with anti-mouse CD103 (clone W19396D) PE (left) or rat IgG2b, κ PE isotype control (right). Cells were costained with anti-mouse CD3 APC.
Compare all formats See PE spectral data
Cat # Size Price Save
110903 25 µg ¥14,080
110904 100 µg ¥40,040
Description

CD103 is the alpha E integrin, which forms a heterodimer with integrin beta 7. The heterodimer complex binds to E-cadherin. It is expressed in on T cells, notably in subpopulations in the lamina propria, on regulatory T cells, or resident memory T cells, and a subset of dendritic cells in gut mucosa. CD103 is thought to be involved with homing to intestinal epithelial sites and has been associated with high levels of TGF-beta presence.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Recombinant mouse integrin alphaE/beta7
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
0.2 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested 
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Clone W19396D can partially block binding of clone 2E7 on target cells.

RRID
AB_2927994 (BioLegend Cat. No. 110903)
AB_2927994 (BioLegend Cat. No. 110904)

Antigen Details

Structure
125 - 150 kD transmembrane glycoprotein, integrin
Distribution

Lamina propria T cells, regulatory T cells, resident memory T cells, subset of dendritic cells

Function
Adhesion, localization and activation of intestinal lymphocytes, lymphocyte homing
Interaction
Integrin β7
Ligand/Receptor
E-Cadherin
Cell Type
Dendritic cells, Lymphocytes, T cells, Tregs
Biology Area
Cell Adhesion, Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References
  1. Parker CM, et al. 1992. Proc Natl Acad Sci U S A. 89:1924-8.
  2. Kruschwitz M, et al. 1991. J Clin Pathol. 44:636-45.
  3. Schon MP, et al. 1999. J. Immunol. 162:6641-9.
  4. Shaw SK, et al. 1994. J Biol Chem. 269:6016-25.
Gene ID
3682 View all products for this Gene ID
UniProt
View information about CD103 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11/17/2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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