PE anti-human HLA-E Antibody

Pricing & Availability
3D12 (See other available formats)
Regulatory Status
Other Names
HLA class I histocompatibility antigen, alpha chain E, HLAE
Mouse IgG1, κ
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Product Citations
Human peripheral blood lymphocytes stained with 3D12 PE
  • 3D12_PE_061909.jpg
    Human peripheral blood lymphocytes stained with 3D12 PE
Compare all formats See PE spectral data
Cat # Size Price Save
342603 25 tests ¥23,760
342604 100 tests ¥57,640

HLA-E is a non-classical MHC class I (MHC-Ib) molecule. It is characterized by limited polymorphism and ubiquitous expression. HLA-E, as other MHC-I molecules, is heterodimerized with β2-microglobulin. HLA-E interacts with CD94/NKG2 receptor to regulate NK cell cytolysis activities.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Antibody Type
Host Species
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Lee N, et al. 1998. Proc. Natl. Acad. Sci. USA. 95:5199.
  2. Wooden SL, et al. 2005. J. Immunol. 175:1383.
  3. Monaco EL, et al. 2008. J. Immunol. 181:5442.
  4. Corrah TW, et al. 2011. J. Virol. 85:3367. PubMed
Product Citations
  1. Nguyen MAT, et al. 2020. Immunohorizons. 0.465277778. PubMed
  2. Leite NC, et al. 2020. Cell Reports. 32(2):107894.. PubMed
  3. Rascle P, et al. 2021. iScience. 24:103109. PubMed
  4. Luetke-Eversloh M, et al. 2014. PLoS Pathog. 10:1004441. PubMed
  5. Suzuki D, et al. 2020. Stem Cell Reports. 14:49. PubMed
  6. Abd Hamid M et al. 2019. Cancer Immunol Res. 7(8):1293-1306 . PubMed
  7. Liang YH, et al. 2021. J Biomed Sci. 28:75. PubMed
AB_1659250 (BioLegend Cat. No. 342603)
AB_1659249 (BioLegend Cat. No. 342604)

Antigen Details

HLA family, Ig superfamily, 42 kD

Broadly expressed

Mediate cell recognition by NK cells
Biology Area
Molecular Family
MHC Antigens
Antigen References

1. Sullivan LC, et al. 2008. Tissue Antigen. 72:415.
2. Koller BH, et al. 1988. J. Immunol. 141:897.

Gene ID
3133 View all products for this Gene ID
View information about HLA-E on

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11/30/2012

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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