PE anti-human CD202b (Tie2/Tek) Antibody

Pricing & Availability
33.1 (Ab33) (See other available formats)
Regulatory Status
Other Names
Tie2, TEK
Mouse IgG1 κ
Ave. Rating
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Product Citations
Human endothelial cell line, HUVEC, stained with 33.1 PE
  • 33dot1_PE_100908.jpg
    Human endothelial cell line, HUVEC, stained with 33.1 PE
See PE spectral data
Cat # Size Price Save
334205 25 tests ¥20,000
334206 100 tests ¥44,000

CD202b is a 145 kD type I transmembrane protein, also known as Tie2 or TEK. It is a member of the receptor tyrosine kinase (RTK) family of proteins and is expressed by endothelial cells and their progenitors, quiescent hematopoietic stem cells (HSCs), and a subpopulation of monocytes. Angiopoietin-1 (Ang-1) is an activator of CD202b to promote, maintain, and stabilize mature vessels and to maintain HSCs in quiescent state. Ang-2 is another ligand of CD202b, which is involved in postnatal angiogenesis and in antagonizing the effects of Ang-1. Tie2 binds to Ang-4 as well.

Product Details
Technical data sheet

Product Details

Antibody Type
Host Species
Recombinant extracellular domain of human Tie2
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications include: immunoprecipitation, Wstern blot, immunohistochemical staining of frozen tissue sections and ELISA

Application References

(PubMed link indicates BioLegend citation)
  1. Peters KG, et al. 1998. Br. J. Cancer. 77:51.
  2. Wong AL, et al. 1997. Circ. Res. 81:567.
  3. Lin P, et al. 1998. P. Natl. Acad. Sci. USA 95:8829.
Product Citations
  1. Adams D, et al. 2014. Proc Natl Acad Sci U S A. 111:3514. PubMed
  2. Kanemaru K, et al. 2015. PLoS One. 10: 0144436. PubMed
AB_1227540 (BioLegend Cat. No. 334205)
AB_2203207 (BioLegend Cat. No. 334206)

Antigen Details

145 kD type I transmembrane protein, receptor tyrosine kinase (RTK) family

Endothelial cells, subsets of hematopoietic stem cells and and a subset of monocytes

Angiogenesis, hemotopoiesis, monocytes chemotaxis
Angiopoietin-1 (Ang-1), Ang-2, and Ang-4
Cell Type
Endothelial cells, Hematopoietic stem and progenitors, Monocytes
Biology Area
Angiogenesis, Cell Biology, Immunology
Molecular Family
CD Molecules
Antigen References

1.De Palma M, et al. 2005. Cancer Cell. 8:211
2.Shaw JP, et al. 2004. Blood Cells Mol. Dis. 32:168
3. Hsu HC, et al. 2000. Blood. 96:3757
4. Arai F, et al. 2004. Cell. 118:149

Gene ID
7010 View all products for this Gene ID
View information about CD202b on

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11/30/2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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