FITC anti-human CD195 (CCR5) Antibody

Pricing & Availability
HEK/1/85a (See other available formats)
Regulatory Status
Other Names
CCR5, C-C chemokine receptor type 5, HIV-1 fusion co-receptor
Rat IgG2a, κ
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Product Citations
Human peripheral blood lymphocytes were stained with CD195 (clone HEK/1/85a) FITC (filled histogram), or rat IgG2a, κ FITC (open histogram).
  • HEK185a_FITC_071607
    Human peripheral blood lymphocytes were stained with CD195 (clone HEK/1/85a) FITC (filled histogram), or rat IgG2a, κ FITC (open histogram).
Compare all formats See FITC spectral data
Cat # Size Price Save
313705 25 tests ¥28,380

CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1α, MIP-1β, and RANTES and is expressed on a subset of T cells and monocytes. CD195 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry; modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Recent studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Antibody Type
Host Species
CHO cells transfected with human CCR5
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Application Notes

Additional reported applications (for the relevant formats) include: immunofluorescence microscopy1

Clone HEK/1/85a and clone HEK/1/85a/7a are the same.

Application References

(PubMed link indicates BioLegend citation)
  1. Mueller A, et al. 2002. Blood 99:785.
  2. Al-Odi E, et al. 2012. PLoS One. 7:e42217. PubMed
  3. Osman A, et al. 2014. J Immunol. 192:5083. PubMed
  4. Liu S, et al. 2014. Virus Res. 192:92. PubMed
Product Citations
  1. Liu S, et al. 2014. Virus Res. 192:92. PubMed
  2. Hinks TSC, et al. 2019. Cell Rep. 28:3249. PubMed
  3. Zhu Y, et al. 2019. Cell Stem Cell. 25:542. PubMed
  4. Li YR, et al. 2021. Cell Rep Med. 2:100449. PubMed
  5. Osman A, et al. 2014. J Immunol. 192:5083. PubMed
  6. Al-ofi E, et al. 2012. PLoS One. 7:e42217. PubMed
AB_345305 (BioLegend Cat. No. 313705)

Antigen Details

G-coupled receptor family 1, membrane protein, 45 kD

Subset of T cells, monocytes

Binds C-C chemokines and transduces an intracellular signal thought to result in proliferation and differentiation. Acts as a co-receptor with CD4 for HIV-1
Cell Type
Dendritic cells, Monocytes, T cells
Biology Area
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors, GPCR
Antigen References

1. Samson M, et al. 1996. Biochemistry 35:3362.
2. Raport CJ, et al. 1996. J. Biol. Chem. 271:17161.
3. Combadiere C, et al. 1996. J. Leukoc. Biol. 60:147.
4. Deng H, et al. 1996. Nature 381:661.
5. Lai J, et al. 2003. CVI. 10:1123.
6. Mañes S, et al. 2003. J. Exp. Med. 198:1381.
7. Vaday GG, et al. 2006. Prostate 66:124.

Gene ID
1234 View all products for this Gene ID
View information about CD195 on

Related FAQs

Does staining at room temperature or even at 37°C help for checking chemokine receptors expression?

Due to continuous recycling of many chemokine receptors, it may be worthwhile to consider staining at room temperature or at 37°C if the staining at lower temperature (which can potentially reduce receptor turnover) is not optimal.

Go To Top Version: 1    Revision Date: 11/30/2012

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • FITC anti-human CD195 (CCR5)

  • PE anti-human CD195 (CCR5)

  • Alexa Fluor® 647 anti-human CD195 (CCR5)

  • Alexa Fluor® 700 anti-human CD195 (CCR5)

  • PerCP/Cyanine5.5 anti-human CD195 (CCR5)

  • Pacific Blue™ anti-human CD195 (CCR5)

  • Purified anti-human CD195 (CCR5)


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