APC anti-human CD159a (NKG2A) Antibody

Pricing & Availability
S19004C (See other available formats)
Regulatory Status
Other Names
Killer Cell Lectin Like Receptor C1, KLRC1, NK Cell Receptor A
Mouse IgG1, κ
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Product Citations
Human peripheral blood lymphocytes were stained with CD3 FITC and CD159a (NKG2A) (clone S19004C) APC (left) or mouse IgG1, κ APC isotype control (right).
  • S19004C_APC_CD159a_Antibody_102620
    Human peripheral blood lymphocytes were stained with CD3 FITC and CD159a (NKG2A) (clone S19004C) APC (left) or mouse IgG1, κ APC isotype control (right).
Compare all formats See APC spectral data
Cat # Size Price Save
375107 25 tests ¥32,780
375108 100 tests ¥86,020

CD159a, also known as NKG2A or KLRC1, is a type II transmembrane protein. It belongs to the killer cell lectin-like receptor family also known as the NKG2 family. It is expressed on NK and NKT cells and T cell subsets. NKG2A is an inhibitory NK cell receptor and it is expressed as a heterodimer with CD94. In human, NKG2A/CD94 complex interacts HLA-E on target cells and inhibits T cells and NK cell effector functions. Recent studies showed that NKG2A blockade enhances the anti-tumor effect of NK cell and CD8+ T cells.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Antibody Type
Host Species
Human NKG2A/CD94-transfectants
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Clone S19004C does not cross-react with mouse CD159a.

Product Citations
  1. Wang H, et al. 2022. Front Immunol. 13:852436. PubMed
  2. Guo M, et al. 2021. Front Oncol. 11:632540. PubMed
AB_2888862 (BioLegend Cat. No. 375107)
AB_2888862 (BioLegend Cat. No. 375108)

Antigen Details

Type II transmembrane proteins of the C-type lectin superfamily

NK cells, NKT cells, T cell subsets

Inhibiting NK cell receptor
Cell Type
Lymphocytes, NK cells, NKT cells, T cells
Biology Area
Immuno-Oncology, Immunology
Molecular Family
Immune Checkpoint Receptors
Antigen References
  1. Brooks AG, et al. 1999. J Immunol. 162:305-13.
  2. Kaiser BK, et al. 2008. Proc Natl Acad Sci U S A. 105: 6696-701.
  3. Braud VM, et al. 2003. Trends Immunol. 24:162-4.
  4. Kamiya T, et al. 2019. J Clin Invest. 129:2094.
  5. André P, et al. 2018. Cell. 175:1731.
Gene ID
3821 View all products for this Gene ID
View information about CD159a on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 10/26/2020

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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