Human

Receptor Main ligand Affinity Cell Distribution
FcεRI IgE Very high Mast cells, Basophils, Monocytes, DCs, Neutrophils
FcεRII (CD23) IgE Low B cells, T cells, NK cells, DCs, Eosinophils, Macrophages
FcγRI (CD64) IgG1> IgG2, IgG3, IgG4 High Monocytes, DCs, Macrophages, Neutrophils , Eosinophils
FcγRIIA (CD32) IgG1 and IgG3>IgG2>IgG4 Low-Medium NK cells, DCs, Macrophages, Monocytes, Neutrophils, Platelets
FcγRIIB* IgG4>IgG1, IgG3>IgG2 Low-Medium Monocytes, DCs, Macrophages, B cells, Neutrophils, Basophils, Mast Cells
FcγRIIC IgG1>IgG3>IgG4>IgG2 Low-Medium NK cells
FcγRIIIA (CD16) IgG1>IgG2 and IgG3>IgG4 Low-Medium Macrophages, NK cells, γδ T cells, Monocytes, DCs
FcγRIIIB IgG1 and IgG3>IgG2 and IgG4 Low-Medium Neutrophils, Mast cells, Eosinophils
FcαRI (CD89) IgA1, IgA2 Low Monocytes, Macrophage and DC subsets, NK cells, Neutrophils, Eosinophils
Fcα/μR IgM>IgA High for IgM, medium for IgA Germinal B cells, Follicular DCs.

*Note that FcγRIIB is actually inhibitory and prevents cell activation. To determine if various cell lines express Fc receptors, you may have to check with the company you purchased it from or the literature.

Mouse

Receptor Main ligand Affinity Cell Distribution
FcεRI IgE Very high Mast cells, Basophils, Monocytes, DCs, Neutrophils
FcεRII (CD23) IgE Low B cells, T cells, NK cells, DCs, Eosinophils, Macrophages
FcγRI (CD64) IgG2a> IgG1, IgG2b, IgG3 High Monocytes, DCs, Macrophages, Neutrophils , Eosinophils
FcγRIIB* IgG1 and IgG2b>IgG2a Low Monocytes, Macrophages, B cells
FcγRIII (CD16) IgG2a and IgG2b>IgG1 Medium NK cells, Macrophages, γδ T cells, Monocyte subsets
FcγRIV IgG2a, IgG2b, and IgE Medium Monocytes, DCs, Neutrophils
Fcα/μR IgM>IgA High for IgM, medium for IgA B cells, Monocytes, and Macrophages

References:

  1. Pleass, R. J. 2011. Parasite Immunol. 31:529. Pubmed
  2. Smith, K.G. and Clatworthy, M.R. 2010. Nat. Rev. Immunol. 10:328. Pubmed