Purified anti-mouse/rat CD61 Antibody

Pricing & Availability
2C9.G2 (HMβ3-1) (See other available formats)
Regulatory Status
Other Names
β3 integrin, Integrin β3 chain, gpIIIa
Armenian Hamster IgG
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Product Citations
C57BL/6 mouse bone marrow cells stained with purified 2C9.G2, followed by anti-Armenian hamster IgG FITC
  • 2C9dotG2_Purified_090707
    C57BL/6 mouse bone marrow cells stained with purified 2C9.G2, followed by anti-Armenian hamster IgG FITC
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104302 500 µg 388€
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CD61 is a 110 kD integrin β chain also known as β3 integrin or gpIIIa. It associates with the integrin αv chain (CD51) to form the vitronectin receptor. In addition, CD61 can associate with the integrin αIIb chain (CD41) to form the gpIIb/IIIa complex. CD61 is expressed on platelets, megakaryocytes, endothelium, smooth muscle, a subset of B cells, myeloid cells, osteoclasts, and mast cells. CD61, in conjunction with CD41 or CD51, mediates adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. Leukocyte-endothelial adhesion is mediated by the binding of αv3 integrin or vitronectin receptor to CD31 (PECAM-1).

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Rat
Antibody Type
Host Species
Armenian Hamster
Vitronectin receptor protein from the mouse T-cell hybridoma 2B4.
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested
IHC - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 104325 and 104326).

Application References

(PubMed link indicates BioLegend citation)
  1. Kieffer N, et al. 1990. Annu. Rev. Cell Biol. 6:329. (Block)
  2. Piali L, et al. 1995. J. Cell Biol. 130:451. (Block)
  3. Ashkar S, et al. 2000. Science 287:860. (Block)
  4. Schultz JF, et al. 1995. J. Biol. Chem. 270:11522. (Block)
  5. Moulder K, et al. 1991. J. Exp. Med. 173:343. (Activ)
  6. Carlson TR, et al. 2008.135:2193. PubMed
  7. Yamaji D, et al. 2009. Genes Dev. 23:2382. PubMed
Product Citations
  1. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  2. Sereni L, et al. 2018. J Allergy Clin Immunol. 142:1272. PubMed
  3. Lagarrigue F, et al. 2018. Blood Adv. 1.720833333. PubMed
  4. Carlson T, et al. 2008. Development. 135:2193. PubMed
AB_313079 (BioLegend Cat. No. 104302)

Antigen Details

Integrin family, 110 kD

Platelets, megakaryocytes, endothelium, smooth muscle, activated T cells, subset of B cells, monocytes, macrophages, osteoclasts, mast cells

Attachment to matrix
Fibrinogen, von Willebrand factor, fibronectin
Cell Type
B cells, Endothelial cells, Macrophages, Mast cells, Megakaryocytes, Monocytes, Osteoclasts, Platelets, T cells
Biology Area
Cell Adhesion, Cell Biology, Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook. Academic Press.
2. Phillips DR, et al. 1991. Cell. 65:359.
3. Felding-Habermann B, et al. 1993. Curr Opinion Cell Biol. 5:864.

Gene ID
16416 View all products for this Gene ID 29302 View all products for this Gene ID
View information about CD61 on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD61 Reagents Request Custom Conjugation
Description Clone Applications
Biotin anti-mouse/rat CD61 2C9.G2 (HMβ3-1) FC
FITC anti-mouse/rat CD61 2C9.G2 (HMβ3-1) FC
PE anti-mouse/rat CD61 2C9.G2 (HMβ3-1) FC
Purified anti-mouse/rat CD61 2C9.G2 (HMβ3-1) FC, IHC
Alexa Fluor® 488 anti-mouse/rat CD61 2C9.G2 (HMβ3-1) FC
Alexa Fluor® 647 anti-mouse/rat CD61 2C9.G2 (HMβ3-1) FC
APC anti-mouse/rat CD61 2C9.G2 (HMβ3-1) FC
PE/Cyanine7 anti-mouse/rat CD61 2C9.G2 (HMβ3-1) FC
PerCP/Cyanine5.5 anti-mouse/rat CD61 2C9.G2 (HMβ3-1) FC
PE/Dazzle™ 594 anti-mouse/rat CD61 2C9.G2 (HMβ3-1) FC
TotalSeq™-C0910 anti-mouse/rat CD61 2C9.G2 (HMβ3-1) PG
Ultra-LEAF™ Purified anti-mouse/rat CD61 2C9.G2 (HMβ3-1) FC, Block, Activ, IHC
TotalSeq™-A0910 anti-mouse/rat CD61 2C9.G2 (HMβ3-1) PG
TotalSeq™-B0910 anti-mouse/rat CD61 2C9.G2 (HMβ3-1) PG
Go To Top Version: 1    Revision Date: 11/30/2012

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • Biotin anti-mouse/rat CD61

  • FITC anti-mouse/rat CD61

  • PE anti-mouse/rat CD61

  • Purified anti-mouse/rat CD61

  • Alexa Fluor® 488 anti-mouse/rat CD61

  • Alexa Fluor® 647 anti-mouse/rat CD61

  • APC anti-mouse/rat CD61

  • PE/Cyanine7 anti-mouse/rat CD61

  • PerCP/Cyanine5.5 anti-mouse/rat CD61

  • PE/Dazzle™ 594 anti-mouse/rat CD61

  • TotalSeq™-C0910 anti-mouse/rat CD61

  • Ultra-LEAF™ Purified anti-mouse/rat CD61

  • TotalSeq™-A0910 anti-mouse/rat CD61

  • TotalSeq™-B0910 anti-mouse/rat CD61


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